<p align="center" style="border: 1px solid rgba(0, 0, 0, 0.1); border-radius: 6px; padding: 30px; box-shadow: 3px 3px 1px 3px rgba(0, 0, 0, 0.1); overflow: auto;"> <a href="/"> <img src="/media/content_files/1/AMDB_logo.png" alt="AMDB logo" width="350px"> </a> </p> <br> # Animal metabolite database Animal metabolite database (AMDB) is a freely accessible database on the quantitative content of metabolites in the tissues of animals. The AMDB is designed to ease browsing and comparing the quantitative metabolomics data and the raw NMR and MS data, as well as the sample metadata. Moreover, the AMDB is a platform, serving the metabolomics community for the convenient deposition and exchange of ‘eternal’ quantitative metabolomics data. The concentrations of most abundant metabolites (typically, 60-90 compounds for each sample) in tissues are obtained mostly with the NMR method and are given in nanomoles per gram of wet tissue weight (nmol/g). To date, the AMDB generally covers the metabolite content of the tissues of vertebrates, primarily wild species from Siberia, Russia as well as laboratory rodents and monkeys, with the focus on the eye lens, although the data on other tissues (blood, muscle, heart, liver, brain, etc.) are also present. The list of [Species](../amdb/taxonomy/tree/) and tissues studied by our group is constantly growing. A [Sample](../amdb/samples/list/) describes information obtained from a certain tissue of a certain individual animal. Each sample contains data on the metabolite concentrations, the raw data from the instrument (NMR or LC-MS), and the metadata (species, age, weight, location, etc.) describing the sample. Samples that are rather uniform i.e. from one species, one tissue, and one disease/factor are combined into [Groups](../amdb/groups/list/) of samples. Sample groups are further compared in completed [Experiments](../amdb/experiments/list/). [Metabolites](../amdb/metabolites/list/) page contains information about the detected and quantified metabolites in the tissues of species, including those identified de-novo in our laboratory. Metabolites also contain links to other databases (PubChem, HMDB, KEGG, ChEBI) if such entry exist in a database. [Currently](../statistics/), AMDB contains 50 species, 14 tissues, 876 samples, 168 quantified metabolites, and more than 50 000 measured concentration values. Information on [How to use the database](/help/) is described in Help/Tutorial page. --- <p style="font-size:14px">The Animal metabolite database (AMDB) is established at the <a href="https://www.tomo.nsc.ru/en/structure/lab/lpm/" target="_blank">Laboratory of Proteomics and Metabolomics</a>, International Tomography Center, Siberian Branch of the Russian Academy of Sciences (ITC SB RAS), and is located in Akademgorodok, Novosibirsk, Russia.</p> <p style="font-size:12px">The AMDB was set up with the financial support from the Russian Foundation for Basic Research (Grant #18-29-13023) and is developing with the financial support from the Russian Scientific Foundation (Grant #22-24-00390)</p>