2-Hydroxybutyric acid


Description:
2-hydroxybutyric acid is a hydroxybutyric acid having a single hydroxyl group located at position 2; urinary secretion of 2-hydroxybutyric acid is increased with alcohol ingestion or vigorous physical exercise and is associated with lactic acidosis and ketoacidosis in humans and diabetes in animals. It has a role as a human metabolite and an algal metabolite. It is a hydroxybutyric acid and a 2-hydroxy monocarboxylic acid. It derives from a butyric acid. It is a conjugate acid of a 2-hydroxybutyrate. Experimental spectrum in Natural Products Magnetic Resonance Database: [NP0000052](https://np-mrd.org/natural_products/446/submission_spectrum_view?spectrum_id=269&spectrum_type=real)

Property Value
Metabolite name 2-Hydroxybutyric acid
AMDB ID 12
PubChem CID 11266
HMDB ID HMDB0000008
KEGG ID C05984
ChEBI ID 50613
Molecular formula C4H8O3
Molecular weight 104.1
Monoisotopic mass 104.047344117
IUPAC name 2-hydroxybutanoic acid

NMR:

Functional group Multiplicity Shift Number of protons
CH3 triplet 0.886 3

Synonyms:

2-hydroxy-butyrate, 2-Hydroxy-butyric acid, 2-OH-butyrate, 2-Hydroxybutyric acid, alpha-hydroxybutyrate, 2-hydroxybutyrate


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