Phosphocholine


Description:
Phosphorylcholine, also known as choline phosphate or CHOP, belongs to the class of organic compounds known as phosphocholines. Phosphocholines are compounds containing a [2-(trimethylazaniumyl)ethoxy]phosphonic acid or derivative. Phosphorylcholine is a moderately acidic compound (based on its pKa). The phosphate of choline; and the parent compound of the Phosphorylcholine family. Phosphorylcholine exists in all living species, ranging from bacteria to humans. Within humans, phosphorylcholine participates in a number of enzymatic reactions. In particular, phosphorylcholine can be converted into choline through its interaction with the enzyme phosphoethanolamine/phosphocholine phosphatase. In addition, phosphorylcholine can be converted into CDP-choline; which is mediated by the enzyme choline-phosphate cytidylyltransferase a. In humans, phosphorylcholine is involved in phospholipid biosynthesis. Outside of the human body, Phosphorylcholine has been detected, but not quantified in, several different foods, such as barley, pak choy, black radish, saskatoon berries, and acorns. This could make phosphorylcholine a potential biomarker for the consumption of these foods.

Property Value
Metabolite name Phosphocholine
AMDB ID 36
PubChem CID 135437
HMDB ID HMDB0001565
KEGG ID N/A
ChEBI ID N/A
Molecular formula C5H14NO4P
Molecular weight 183.14
Monoisotopic mass 183.06604493
IUPAC name 2-(trimethylazaniumyl)ethyl hydrogen phosphate

Synonyms:

Phosphocholine, Phosphorylcholine, PhCholine, O-phosphocholine


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