4-Aminobutyric acid


Description:
Gamma-Aminobutyric Acid (GABA) is a naturally occurring neurotransmitter with central nervous system (CNS) inhibitory activity. Gamma-aminobutyric acid, converted from the principal excitatory neurotransmitter glutamate in the brain, plays a role in regulating neuronal excitability by binding to its receptors, GABA-A and GABA-B, and thereby causing ion channel opening, hyperpolarization and eventually inhibition of neurotransmission. Experimental spectrum in Natural Products Magnetic Resonance Database: [NP0000970](https://np-mrd.org/natural_products/395/submission_spectrum_view?spectrum_id=230&spectrum_type=real)

Property Value
Metabolite name 4-Aminobutyric acid
AMDB ID 74
PubChem CID 119
HMDB ID HMDB0000112
KEGG ID C00334
ChEBI ID 16865
Molecular formula C4H9NO2
Molecular weight 103.12
Monoisotopic mass 103.063328534
IUPAC name 4-aminobutanoic acid

NMR:

Functional group Multiplicity Shift Number of protons
CH2 multiplet 1.89 2
CH2 triplet 2.284 2
CH2 triplet 3.001 2

Synonyms:

GABA, gamma-aminobutyric acid, 4-aminobutyric acid, γ-aminobutyric acid, γ-aminobutyrate, Gamma-aminobutyrate


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