Hypoxanthine is a purine-based organic compound in human muscle tissues, Hypoxanthine is formed during purine catabolism as a product of xanthine oxidase action on xanthine, and occasionally is found as a constituent of nucleic acids. The potent anti-inflammatory and cytoprotective effects of purines may be mediated by cell surface adenosine receptors. Hypoxanthine protects against oxidant-induced cell injury by inhibiting activation of nuclear poly(ADP-ribose) polymerase (PARP). (NCI04)
Property | Value |
---|---|
Metabolite name | Hypoxanthine |
AMDB ID | 78 |
PubChem CID | 135398638 |
HMDB ID | HMDB0000157 |
KEGG ID | N/A |
ChEBI ID | N/A |
Molecular formula | C5H4N4O |
Molecular weight | 136.11 |
Monoisotopic mass | 136.038510766 |
IUPAC name | 1,7-dihydropurin-6-one |
Hypoxanthine, 6-Hydroxypurine