| Property | Value |
|---|---|
| Experiment name | Mice brain with phospholipids treatment |
| Experiment ID | 239 |
| Sample groups | C57Bl/6 brain PL, C57Bl/6 brain control |
| Species | House mouse (Mus musculus) |
| Tissues | Brain |
| Diseases | N/A |
| Date of creation | 16:59, Nov 14, 2022 |
| Date of last modification | 16:59, Nov 14, 2022 |
| Author | y.tsentalovich |
| Metabolites / Groups | C57Bl/6 brain PL | C57Bl/6 brain control |
|---|---|---|
| 1-Methylhistidine | 84.9 ± 16.2 | 83.0 ± 8.0 |
| 2-Hydroxy-3-methylbutyric acid | 7.9 ± 1.6 | 10.0 ± 2.5 |
| 2-Hydroxyisobutyric acid | 6.2 ± 1.6 | 6.8 ± 1.5 |
| 3-Hydroxybutyric acid | 15.7 ± 10.2 | 19.0 ± 6.4 |
| 4-Aminobutyric acid | 5104.2 ± 856.9 | 5005.9 ± 736.7 |
| Acetic acid | 964.7 ± 205.6 | 929.9 ± 141.7 |
| Acetylcarnitine | 115.2 ± 136.2 | 121.2 ± 140.2 |
| Adenosine | 347.8 ± 63.9 | 382.2 ± 66.3 |
| ADP | 93.3 ± 22.9 | 111.3 ± 23.3 |
| AMP | 533.5 ± 220.4 | 692.8 ± 251.2 |
| Anserine | 826.0 ± 110.4 | 852.3 ± 86.8 |
| Ascorbic acid | 1352.9 ± 279.8 | 1418.9 ± 152.7 |
| Asparagine | 126.9 ± 17.2 | 122.1 ± 31.0 |
| Aspartic acid | 4669.9 ± 823.2 | 4949.5 ± 426.9 |
| ATP | 14.3 ± 6.3 | 18.7 ± 11.1 |
| beta-Alanine | 874.0 ± 129.9 | 909.4 ± 120.4 |
| Betaine | 1583.4 ± 329.6 | 1579.7 ± 210.6 |
| Choline | 802.8 ± 184.3 | 758.9 ± 146.9 |
| CMP | 31.0 ± 12.0 | 21.0 ± 11.4 |
| Creatine | 10397.6 ± 1836.5 | 10894.7 ± 1071.6 |
| Formic acid | 317.4 ± 90.9 | 301.6 ± 35.2 |
| Fumaric acid | 160.9 ± 30.8 | 159.2 ± 37.1 |
| Glutamic acid | 9477.7 ± 2073.6 | 10141.0 ± 1236.9 |
| Glutamine | 4915.1 ± 951.8 | 4907.9 ± 540.1 |
| Glycerol | 925.6 ± 182.6 | 878.0 ± 229.9 |
| Glycerophosphocholine | 743.6 ± 363.1 | 803.3 ± 339.3 |
| GSH | 593.3 ± 202.4 | 566.7 ± 208.2 |
| GSSG | 58.8 ± 18.7 | 58.5 ± 7.4 |
| GTP | 64.4 ± 16.4 | 58.5 ± 16.5 |
| Hypotaurine | 11551.0 ± 2047.4 | 12021.2 ± 1432.7 |
| IMP | 830.8 ± 266.4 | 800.6 ± 212.8 |
| Isoleucine | 60.4 ± 11.0 | 59.8 ± 10.4 |
| Ketoleucine | 150.6 ± 46.9 | 142.1 ± 29.5 |
| Lactic acid | 10655.9 ± 1965.0 | 11609.1 ± 766.8 |
| myo-Inositol | 7633.1 ± 1312.5 | 8086.6 ± 747.5 |
| N-acetylaspartic acid | 5651.5 ± 1029.1 | 5950.0 ± 555.1 |
| N-acetyltyrosine | 96.8 ± 22.3 | 86.4 ± 18.1 |
| NAD | 6.9 ± 2.6 | 12.0 ± 5.9 |
| NADH | 18.1 ± 5.7 | 14.8 ± 4.1 |
| NADPH | 375.4 ± 82.1 | 379.9 ± 51.2 |
| Pantothenic acid | 33.6 ± 6.0 | 31.5 ± 5.6 |
| Phenylalanine | 116.0 ± 22.2 | 119.3 ± 21.3 |
| Phosphoethanolamine | 1308.7 ± 206.1 | 1341.2 ± 113.5 |
| Propylene glycol | 23.0 ± 42.6 | 8.7 ± 7.1 |
| Pyruvic acid | 31.5 ± 14.9 | 26.5 ± 5.8 |
| scyllo-Inositol | 96.7 ± 30.4 | 96.8 ± 32.8 |
| Succinic acid | 238.2 ± 41.2 | 236.9 ± 51.7 |
| Threonine | 337.0 ± 90.8 | 317.0 ± 43.2 |
| Tryptophan | 39.0 ± 3.6 | 43.3 ± 26.0 |
| Uracil | 57.7 ± 10.2 | 54.0 ± 8.1 |
| UTP | 167.9 ± 27.2 | 169.2 ± 14.0 |
| Valine | 124.9 ± 27.2 | 126.2 ± 25.3 |
| Metabolites / Samples | B7 | B8 | B9 | B10 | B11 | B12 | B1 | B2 | B3 | B4 | B5 | B6 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1-Methylhistidine | 75.5 | 75.0 | 102.1 | 102.9 | 63.2 | 90.6 | 72.4 | 75.0 | 82.8 | 92.5 | 85.6 | 89.9 |
| 2-Hydroxy-3-methylbutyric acid | 9.9 | 7.3 | 8.7 | 5.2 | 7.8 | 8.4 | 5.5 | 11.4 | 10.7 | 11.1 | 12.5 | 9.1 |
| 2-Hydroxyisobutyric acid | 8.0 | 6.0 | 7.6 | 4.8 | 4.0 | 6.9 | 7.9 | 5.3 | 7.5 | 8.5 | 6.8 | 4.7 |
| 3-Hydroxybutyric acid | 29.9 | 7.3 | 3 | 13.9 | 15.4 | 24.8 | 27.3 | 25.0 | 11.6 | 20.8 | 15.4 | 13.9 |
| 4-Aminobutyric acid | 5177.4 | 4397.5 | 5542.7 | 6030.4 | 3777.0 | 5700.4 | 4857.6 | 4533.5 | 4660.7 | 6491.8 | 4689.0 | 4803.2 |
| Acetic acid | 1047.6 | 754.1 | 1008.7 | 1197.8 | 674.6 | 1105.2 | 901.6 | 764.6 | 855.0 | 1182.4 | 974.9 | 901.1 |
| Acetylcarnitine | 32.9 | 283.2 | 298.5 | 33.8 | 19.2 | 23.8 | 43.7 | 285.4 | 317.5 | 27.2 | 31.9 | 21.6 |
| Adenosine | 453.6 | 318.3 | 400.2 | 305.8 | 311.3 | 297.9 | 345.8 | 381.7 | 362.4 | 470.8 | 443.4 | 289.2 |
| ADP | 79.2 | 90.3 | 136.5 | 96.2 | 71.1 | 86.1 | 109.9 | 99.7 | 153.7 | 118.7 | 98.2 | 87.6 |
| AMP | 600.3 | 669.5 | 858.6 | 473.9 | 321.6 | 277.1 | 852.0 | 759.9 | 1073.6 | 517.1 | 568.6 | 385.5 |
| Anserine | 810.3 | 744.8 | 961.1 | 909.5 | 661.5 | 869.0 | 777.0 | 830.8 | 912.3 | 999.3 | 809.2 | 785.4 |
| Ascorbic acid | 1434.4 | 1311.4 | 1705.3 | 1562.9 | 922.3 | 1181.3 | 1417.7 | 1399.7 | 1538.6 | 1635.7 | 1310.7 | 1211.1 |
| Asparagine | 141.7 | 117.2 | 137.4 | 140.7 | 97.6 | 126.6 | 101.2 | 114.2 | 137.6 | 172.5 | 83.1 | 123.9 |
| Aspartic acid | 4862.4 | 4210.1 | 5149.0 | 5671.1 | 3297.8 | 4829.4 | 4925.7 | 4372.3 | 5490.8 | 5384.2 | 4874.3 | 4649.8 |
| ATP | 4.6 | 20.4 | 12.9 | 11.1 | 15.3 | 21.4 | 14.3 | 16.6 | 41.0 | 16.3 | 13.8 | 10.4 |
| beta-Alanine | 879.2 | 815.6 | 904.9 | 1029.4 | 654.3 | 960.7 | 868.3 | 875.5 | 915.6 | 1145.2 | 821.4 | 830.4 |
| Betaine | 1688.5 | 1244.7 | 1878.9 | 1937.2 | 1132.0 | 1619.1 | 1475.8 | 1406.2 | 1593.5 | 1987.8 | 1550.1 | 1464.8 |
| Choline | 806.1 | 607.6 | 866.4 | 1036.3 | 566.5 | 934.1 | 708.5 | 614.8 | 675.0 | 1024.7 | 706.8 | 823.6 |
| CMP | 15.4 | 31.6 | 50.9 | 36.1 | 25.5 | 26.5 | 10.3 | 12.1 | 12.8 | 39.8 | 25.0 | 25.8 |
| Creatine | 11059.6 | 9655.1 | 12380.5 | 11907.5 | 7305.7 | 10077.1 | 10546.7 | 10605.0 | 11533.6 | 12694.4 | 10360.2 | 9628.2 |
| Formic acid | 417.4 | 413.8 | 312.1 | 332.6 | 198.0 | 230.5 | 309.4 | 344.2 | 251.6 | 333.9 | 296.7 | 274.0 |
| Fumaric acid | 169.3 | 152.4 | 196.1 | 189.9 | 113.6 | 144.1 | 166.0 | 117.6 | 139.9 | 227.3 | 152.7 | 151.6 |
| Glutamic acid | 10027.6 | 9378.5 | 12113.6 | 10952.5 | 6285.9 | 8108.4 | 10288.8 | 9843.2 | 11217.0 | 11705.1 | 9541.7 | 8250.1 |
| Glutamine | 5096.1 | 4738.6 | 6184.2 | 5463.8 | 3335.5 | 4672.4 | 4621.9 | 4968.6 | 4936.4 | 5897.6 | 4710.2 | 4313.0 |
| Glycerol | 978.6 | 717.1 | 994.7 | 1151.8 | 690.2 | 1021.3 | 704.8 | 742.3 | 763.5 | 1326.9 | 842.4 | 888.0 |
| Glycerophosphocholine | 1016.1 | 876.5 | 437.7 | 1198.0 | 705.2 | 228.2 | 943.6 | 936.1 | 603.3 | 1209.0 | 894.7 | 233.0 |
| GSH | 514.2 | 588.8 | 980.9 | 468.9 | 412.1 | 594.5 | 447.6 | 492.2 | 742.6 | 903.9 | 432.7 | 381.2 |
| GSSG | 54.8 | 47.4 | 91.0 | 62.0 | 35.4 | 62.0 | 59.9 | 58.2 | 63.5 | 68.9 | 51.3 | 49.3 |
| GTP | 67.2 | 47.7 | 62.3 | 86.0 | 44.9 | 78.6 | 45.1 | 47.0 | 41.2 | 82.8 | 67.0 | 68.1 |
| Hypotaurine | 12314.8 | 10995.2 | 13834 | 13062.7 | 8039.9 | 11059.2 | 11663.0 | 11222.6 | 13229.6 | 14274.4 | 11259.2 | 10478.7 |
| IMP | 862.0 | 664.4 | 983.7 | 1095.4 | 379.1 | 1000.1 | 755.4 | 545.2 | 808.7 | 1146.8 | 636.2 | 911.2 |
| Isoleucine | 61.6 | 51.7 | 60.0 | 71.0 | 44.7 | 73.5 | 60.5 | 50.0 | 44.8 | 70.5 | 63.1 | 69.7 |
| Ketoleucine | 143.5 | 120.3 | 145.6 | 188.7 | 87.3 | 218.1 | 142.1 | 116.4 | 106.7 | 188.2 | 159.6 | 139.8 |
| Lactic acid | 11603.1 | 10301.4 | 12293.5 | 12765.6 | 7555.4 | 9416.3 | 11759.3 | 11510.0 | 11641.8 | 12887.6 | 11342.8 | 10513.2 |
| myo-Inositol | 8202.4 | 6829.2 | 9127.6 | 8608.9 | 5525.7 | 7504.6 | 8249.8 | 7825.5 | 8752.3 | 9039.1 | 7637.2 | 7015.8 |
| N-acetylaspartic acid | 5937.6 | 5421.8 | 6967.8 | 6289.8 | 3939.5 | 5352.6 | 5915.4 | 5786.4 | 6453.6 | 6624.4 | 5863.2 | 5057.3 |
| N-acetyltyrosine | 97.6 | 79.3 | 88.7 | 113.5 | 70.8 | 131.0 | 84.4 | 66.4 | 79 | 120.6 | 83.1 | 84.6 |
| NAD | 3.8 | 7.6 | 9.8 | 8.5 | 8.1 | 3.5 | 17.8 | 9.8 | 16.6 | 7.4 | 16.8 | 3.6 |
| NADH | 14.2 | 21.0 | 24.5 | 23.2 | 10.1 | 15.4 | 7.9 | 20.1 | 14.0 | 16.5 | 16.5 | 13.5 |
| NADPH | 386.4 | 405.0 | 418.3 | 469.6 | 230.8 | 342.2 | 379.8 | 369 | 395.3 | 457.9 | 298.1 | 379.3 |
| Pantothenic acid | 39.7 | 26.4 | 38.2 | 36.9 | 26.1 | 34.2 | 32.3 | 24.7 | 34.4 | 39.3 | 32.8 | 25.4 |
| Phenylalanine | 125.4 | 112.2 | 115.7 | 148.6 | 80.1 | 114.1 | 112.4 | 102.8 | 103.9 | 158.3 | 109.5 | 128.6 |
| Phosphoethanolamine | 1385.7 | 1394.9 | 1468.7 | 1374.8 | 898 | 1330.0 | 1373.7 | 1432.0 | 1452.5 | 1389.2 | 1183 | 1217.2 |
| Propylene glycol | 109.8 | 8.4 | 5.0 | 4.5 | 2.9 | 7.4 | 15.4 | 5.7 | 19.3 | 7.1 | 2.9 | 1.6 |
| Pyruvic acid | 28.1 | 26.4 | 27.1 | 61.5 | 21.7 | 24.3 | 30.4 | 35.2 | 24.4 | 23.5 | 27.4 | 18.4 |
| scyllo-Inositol | 68.3 | 106.4 | 130.6 | 132.2 | 67.7 | 75 | 70.1 | 67.9 | 67.8 | 132.3 | 137.8 | 104.5 |
| Succinic acid | 197.6 | 229.3 | 309.1 | 240.1 | 199.3 | 253.6 | 165.0 | 241.3 | 290.8 | 292.1 | 242.3 | 189.7 |
| Threonine | 352.0 | 279.6 | 463.5 | 409.7 | 213.4 | 303.9 | 327.3 | 270.3 | 281.5 | 392.3 | 321.8 | 308.8 |
| Tryptophan | 38.6 | 39.8 | 38.5 | 45.4 | 34.4 | 37.2 | 31.7 | 28.4 | 29.9 | 76.4 | 17.2 | 76.1 |
| Uracil | 51.8 | 51.0 | 54.6 | 77.6 | 51.8 | 59.5 | 46.0 | 58.5 | 44.8 | 65.9 | 51.3 | 57.4 |
| UTP | 169.8 | 138.7 | 173.6 | 198.2 | 133.1 | 193.9 | 156.4 | 180.8 | 164.1 | 192.0 | 161.9 | 160.1 |
| Valine | 124.7 | 107.2 | 136.4 | 166.0 | 85.8 | 129.4 | 122.9 | 93.6 | 120.2 | 171.8 | 126.8 | 121.8 |
| Properties / Samples | B7 | B8 | B9 | B10 | B11 | B12 | B1 | B2 | B3 | B4 | B5 | B6 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Group | C57Bl/6 brain PL | C57Bl/6 brain PL | C57Bl/6 brain PL | C57Bl/6 brain PL | C57Bl/6 brain PL | C57Bl/6 brain PL | C57Bl/6 brain con… | C57Bl/6 brain con… | C57Bl/6 brain con… | C57Bl/6 brain con… | C57Bl/6 brain con… | C57Bl/6 brain con… |
| Description | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Species | House mouse (Mus … | House mouse (Mus … | House mouse (Mus … | House mouse (Mus … | House mouse (Mus … | House mouse (Mus … | House mouse (Mus … | House mouse (Mus … | House mouse (Mus … | House mouse (Mus … | House mouse (Mus … | House mouse (Mus … |
| Tissue | Brain | Brain | Brain | Brain | Brain | Brain | Brain | Brain | Brain | Brain | Brain | Brain |
| Diseases | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Gender | male | male | male | male | male | male | male | male | male | male | male | male |
| Origin | laboratory | laboratory | laboratory | laboratory | laboratory | laboratory | laboratory | laboratory | laboratory | laboratory | laboratory | laboratory |
| Sample weight, mg | 163.5 | 168.9 | 166.7 | 136.0 | 166.5 | 165.1 | 165.0 | 137.3 | 179.1 | 172.7 | 162.4 | 170.3 |
| Sampling place | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia |
| Sampling date | Sept. 4, 2021 | Sept. 4, 2021 | Sept. 4, 2021 | Sept. 4, 2021 | Sept. 4, 2021 | Sept. 4, 2021 | Sept. 4, 2021 | Sept. 4, 2021 | Sept. 4, 2021 | Sept. 4, 2021 | Sept. 4, 2021 | Sept. 4, 2021 |
| Time postmortem, min | 10 | 10 | 10 | 10 | 10 | 10 | 10 | 10 | 10 | 10 | 10 | 10 |