| Property | Value |
|---|---|
| Experiment name | Porcine lens |
| Experiment ID | 193 |
| Sample groups | Porcine lens intact, Porcine lens irr |
| Species | Domestic pig (Sus scrofa domesticus) |
| Tissues | Lens |
| Diseases | N/A |
| Date of creation | 17:10, Aug 19, 2021 |
| Date of last modification | 18:13, Jun 09, 2023 |
| Author | y.tsentalovich |
| Metabolites / Groups | Porcine lens intact | Porcine lens irr |
|---|---|---|
| 2-Aminobutyric acid | 24.9 ± 9.5 | 25.0 ± 8.4 |
| 2-Hydroxy-3-methylbutyric acid | 13.1 ± 4.7 | 12.0 ± 4.5 |
| 4-Aminobutyric acid | 746.2 ± 450.2 | 821.1 ± 329.0 |
| Acetic acid | 565.8 ± 76.4 | 651.3 ± 92.9 |
| ADP | 134.0 ± 33.5 | 157.6 ± 23.1 |
| Alanine | 1460.0 ± 413.1 | 1485.4 ± 460.7 |
| AMP | 277.7 ± 49.2 | 290.6 ± 53.9 |
| Ascorbic acid | 537.8 ± 77.3 | 509.4 ± 47.1 |
| ATP | 531.6 ± 128.6 | 595.9 ± 54.8 |
| Betaine | 128.5 ± 62.8 | 142.1 ± 40.9 |
| Carnitine | 99.5 ± 22.5 | 108.0 ± 15.5 |
| Choline | 238.8 ± 66.6 | 184.7 ± 42.6 |
| Citric acid | 367.0 ± 73.1 | 392.4 ± 46.3 |
| Creatine | 301.6 ± 69.6 | 296.9 ± 37.0 |
| Ergothioneine | 49.0 ± 13.3 | 50.4 ± 15.9 |
| Formic acid | 90.1 ± 50.8 | 103.7 ± 66.2 |
| Fumaric acid | 1.4 ± 1.1 | 1.2 ± 0.5 |
| Glutamic acid | 2104.0 ± 416.5 | 2243.3 ± 234.6 |
| Glutamine | 499.9 ± 129.7 | 478.5 ± 136.7 |
| Glycerophosphocholine | 359.6 ± 71.0 | 424.0 ± 126.2 |
| Glycine | 427.1 ± 120.2 | 409.7 ± 90.7 |
| GSH | 5353.8 ± 711.9 | 5212.3 ± 621.3 |
| GSSG | 165.0 ± 48.0 | 190.8 ± 58.2 |
| Histidine | 87.2 ± 25.4 | 80.4 ± 13.1 |
| Hypotaurine | 1168.0 ± 415.4 | 1138.1 ± 421.1 |
| Hypoxanthine | 78.3 ± 14.0 | 83.4 ± 34.0 |
| IMP | 37.2 ± 27.7 | 29.2 ± 12.1 |
| Inosine | 136.2 ± 25.4 | 117.0 ± 14.9 |
| Isobutyric acid | 2.4 ± 0.6 | 2.3 ± 0.2 |
| Isoleucine | 194.1 ± 58.4 | 187.2 ± 55.2 |
| Ketoleucine | 1.7 ± 0.8 | 1.7 ± 0.6 |
| Leucine | 363.2 ± 86.8 | 383.7 ± 72.8 |
| L-Lactic acid | 6433.7 ± 1043.9 | 6537.2 ± 225.1 |
| Methionine | 61.9 ± 12.2 | 60.4 ± 12.7 |
| myo-Inositol | 11450.0 ± 2490.8 | 11050.4 ± 1258.6 |
| NAD | 95.2 ± 53.8 | 106.7 ± 67.4 |
| NADH | 6.2 ± 3.3 | 4.7 ± 0.7 |
| Phenylalanine | 220.3 ± 45.0 | 199.1 ± 33.8 |
| Phosphocholine | 473.4 ± 100.1 | 501.2 ± 84.6 |
| Phosphoethanolamine | 552.3 ± 177.3 | 555.1 ± 72.0 |
| Propylene glycol | 15.0 ± 5.8 | 16.6 ± 5.0 |
| Pyroglutamic acid | 864.7 ± 142.3 | 844.2 ± 63.6 |
| scyllo-Inositol | 1266.8 ± 74.2 | 1295.0 ± 248.9 |
| Taurine | 2626.5 ± 1096.1 | 2685.3 ± 1048.0 |
| Tryptophan | 81.4 ± 15.7 | 75.5 ± 13.9 |
| Tyrosine | 253.1 ± 47.2 | 255.9 ± 33.5 |
| Uracil | 14.1 ± 3.5 | 17.0 ± 6.0 |
| Valine | 474.2 ± 126.3 | 464.3 ± 119.8 |
| Metabolites / Samples | PLS1 | PLS2 | PLS3 | PLS4 | PLS5 | PLS6 | PLS7 | PLirS1 | PLirS2 | PLirS3 | PLirS4 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 2-Aminobutyric acid | 31.9 | 19.7 | 40.4 | 16.4 | 29.3 | 13.9 | 22.5 | 21.9 | 23.7 | 36.9 | 17.4 |
| 2-Hydroxy-3-methylbutyric acid | 19.4 | 11.2 | 14.9 | 7.1 | 17.4 | 7.5 | 14.2 | 16.4 | 9.4 | 15.2 | 7.0 |
| 4-Aminobutyric acid | 1507.3 | 588.0 | 1238.7 | 359.7 | 534.2 | 337.4 | 658.6 | 993.0 | 738.6 | 1153.5 | 399.3 |
| Acetic acid | 693.5 | 589.6 | 604.5 | 464.8 | 507.8 | 514.2 | 585.8 | 731.3 | 712.3 | 635.0 | 526.8 |
| ADP | 115.4 | 118.4 | 171.5 | 190.3 | 100.9 | 127.7 | 113.5 | 139.6 | 139.0 | 187.4 | 164.2 |
| Alanine | 1609.7 | 1252.0 | 2250.7 | 1025.7 | 1607.9 | 1129.2 | 1345.0 | 1206.8 | 1552.2 | 2107.2 | 1075.5 |
| AMP | 264.2 | 225.1 | 349.2 | 257.9 | 223.9 | 290.8 | 332.6 | 220.1 | 348.8 | 308.8 | 284.8 |
| Ascorbic acid | 600.9 | 474.2 | 535.0 | 411.4 | 537.6 | 561.4 | 643.9 | 499.5 | 568.2 | 515.9 | 454.0 |
| ATP | 708.9 | 541.3 | 615.6 | 437.4 | 331.7 | 467.2 | 619 | 574.9 | 632.8 | 647.4 | 528.3 |
| Betaine | 230.2 | 78.6 | 197.0 | 104.3 | 58.3 | 103.8 | 127.0 | 172.0 | 99.8 | 181.9 | 114.5 |
| Carnitine | 125.3 | 90.4 | 111.9 | 73.4 | 81.2 | 85.0 | 129.6 | 95 | 126.9 | 114.6 | 95.5 |
| Choline | 224.9 | 250.7 | 146.2 | 200.6 | 265.3 | 221.5 | 362.2 | 184.5 | 245 | 155.9 | 153.3 |
| Citric acid | 469.3 | 331.3 | 439.3 | 280.7 | 364.8 | 285.3 | 398.2 | 388.9 | 418.4 | 433.5 | 328.9 |
| Creatine | 362.8 | 254.2 | 293.7 | 269.0 | 213.8 | 297.0 | 420.8 | 337.2 | 304.7 | 297.9 | 247.7 |
| Ergothioneine | 44.2 | 40.4 | 77.5 | 39.6 | 42.1 | 51.8 | 47.8 | 38.6 | 48.1 | 73.4 | 41.4 |
| Formic acid | 198.0 | 76.7 | 51.4 | 57.6 | 57.3 | 95.0 | 95.1 | 199.0 | 98.4 | 61.2 | 56.3 |
| Fumaric acid | 3.6 | 2.1 | 1.1 | 1.0 | 0.8 | 0.9 | 0.5 | 1.9 | 1.2 | 0.9 | 0.8 |
| Glutamic acid | 2461.1 | 1769.9 | 2583.9 | 1638.9 | 1706.6 | 2026.0 | 2541.3 | 2124.1 | 2420 | 2457.4 | 1971.7 |
| Glutamine | 317.3 | 400.4 | 592.3 | 558.7 | 399.0 | 681.7 | 550.0 | 320.5 | 438.2 | 647.5 | 507.7 |
| Glycerophosphocholine | 389.4 | 390.9 | 355.6 | 326.1 | 264.4 | 307.1 | 483.7 | 334.9 | 610.4 | 361.4 | 389.5 |
| Glycine | 540.5 | 302.4 | 424.2 | 341.8 | 524 | 284.2 | 572.5 | 537.9 | 375.3 | 399.0 | 326.5 |
| GSH | 5665.7 | 4907.8 | 5874.9 | 4564.0 | 4529.3 | 5511.1 | 6423.7 | 4346.7 | 5820.0 | 5396.4 | 5285.9 |
| GSSG | 242.3 | 146.9 | 130.7 | 116.4 | 153.0 | 142.6 | 223.0 | 256.4 | 207.7 | 182.4 | 116.7 |
| Histidine | 79.0 | 61.5 | 96.4 | 71.4 | 88.7 | 74.9 | 138.9 | 68.5 | 81.3 | 98.4 | 73.5 |
| Hypotaurine | 1690.7 | 932.8 | 1729.9 | 620.1 | 1044.1 | 906.9 | 1251.9 | 1084.7 | 1069.8 | 1707.4 | 690.4 |
| Hypoxanthine | 88.7 | 63.0 | 59.7 | 69.6 | 86.1 | 85.8 | 95.4 | 134.0 | 71.7 | 64.3 | 63.4 |
| IMP | 33.0 | 19.4 | 22.0 | 18.8 | 97.3 | 29.2 | 40.5 | 47.1 | 20.7 | 26.5 | 22.6 |
| Inosine | 157.9 | 97.2 | 163.7 | 110.3 | 157.2 | 131.3 | 135.9 | 134.8 | 113.8 | 120.7 | 98.8 |
| Isobutyric acid | 3.5 | 1.7 | 2.4 | 1.6 | 2.4 | 2.4 | 2.7 | 2.5 | 2.1 | 2.6 | 2.3 |
| Isoleucine | 251.1 | 139.0 | 258.6 | 116.2 | 195.1 | 155.3 | 243.7 | 210.7 | 170.7 | 248.1 | 119.3 |
| Ketoleucine | 2.9 | 2.4 | 1.9 | 1.0 | 1.3 | 0.7 | 2.0 | 2.3 | 2.0 | 1.8 | 0.9 |
| Leucine | 436.6 | 284.7 | 465.3 | 276.0 | 389.7 | 260.8 | 429.6 | 428.4 | 365.0 | 451.9 | 289.3 |
| L-Lactic acid | 7773.3 | 5140.1 | 6911.9 | 5650.8 | 5880.8 | 5946.8 | 7732.3 | 6810.3 | 6506.1 | 6569.7 | 6262.5 |
| Methionine | 54.7 | 54.0 | 84.8 | 55.1 | 71.1 | 50.7 | 63.0 | 55.6 | 50.7 | 79.1 | 56.3 |
| myo-Inositol | 13221.4 | 10255.4 | 10630.4 | 9553.9 | 11379.3 | 8953.1 | 16156.6 | 9974.4 | 12809.1 | 10342.6 | 11075.5 |
| NAD | 209.7 | 84.2 | 56.7 | 62.7 | 55.9 | 96.8 | 100.6 | 202.8 | 104.2 | 60.5 | 59.3 |
| NADH | 3.7 | 3.5 | 5.4 | 5.5 | 13.2 | 5.4 | 6.4 | 4.5 | 5.0 | 3.8 | 5.6 |
| Phenylalanine | 262.6 | 164.4 | 226.2 | 156.9 | 246.2 | 215.8 | 270.4 | 234.5 | 193.8 | 213.1 | 154.9 |
| Phosphocholine | 570.3 | 413.5 | 616.3 | 342.4 | 396.2 | 447.8 | 527.5 | 453 | 529.3 | 606.6 | 416.0 |
| Phosphoethanolamine | 814.7 | 439.6 | 624.9 | 342.7 | 376.4 | 551.1 | 716.5 | 505.8 | 605.4 | 627.4 | 481.9 |
| Propylene glycol | 20.4 | 10.4 | 13.2 | 15.4 | 7.1 | 24.3 | 14.3 | 19.5 | 9.2 | 20.2 | 17.3 |
| Pyroglutamic acid | 894.8 | 670.6 | 966.4 | 709.2 | 906.5 | 827.7 | 1077.4 | 760.3 | 861.7 | 913.3 | 841.6 |
| scyllo-Inositol | 1315.0 | 1235.6 | 1314.3 | 1172.0 | 1290.2 | 1364.9 | 1175.8 | 976.4 | 1540.8 | 1228.1 | 1434.6 |
| Taurine | 4056.6 | 1659.0 | 4201.0 | 1660.2 | 1732.6 | 2540.4 | 2535.8 | 2700.0 | 1989.6 | 4161.3 | 1890.2 |
| Tryptophan | 85.7 | 64.2 | 85.6 | 55.9 | 87.9 | 89.7 | 100.9 | 82.6 | 69.2 | 90.8 | 59.6 |
| Tyrosine | 319.6 | 213.4 | 275.2 | 212.4 | 265.9 | 193.3 | 291.7 | 293.0 | 257.6 | 261.1 | 211.8 |
| Uracil | 21.4 | 11.9 | 11.5 | 12.7 | 15.1 | 14.2 | 12.3 | 25.6 | 12 | 13.9 | 16.6 |
| Valine | 563.7 | 370.7 | 639.3 | 301.8 | 519.4 | 368.6 | 556.3 | 461.8 | 463.4 | 612.8 | 319.4 |
| Properties / Samples | PLS1 | PLS2 | PLS3 | PLS4 | PLS5 | PLS6 | PLS7 | PLirS1 | PLirS2 | PLirS3 | PLirS4 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Group | Porcine lens inta… | Porcine lens inta… | Porcine lens inta… | Porcine lens inta… | Porcine lens inta… | Porcine lens inta… | Porcine lens inta… | Porcine lens irr | Porcine lens irr | Porcine lens irr | Porcine lens irr |
| Description | control | control | control | control | control | control | control | uv-irradiated | uv-irradiated | uv-irradiated | uv-irradiated |
| Species | Domestic pig (Sus… | Domestic pig (Sus… | Domestic pig (Sus… | Domestic pig (Sus… | Domestic pig (Sus… | Domestic pig (Sus… | Domestic pig (Sus… | Domestic pig (Sus… | Domestic pig (Sus… | Domestic pig (Sus… | Domestic pig (Sus… |
| Tissue | Lens | Lens | Lens | Lens | Lens | Lens | Lens | Lens | Lens | Lens | Lens |
| Diseases | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Gender | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Origin | farm | farm | farm | farm | farm | farm | farm | farm | farm | farm | farm |
| Sample weight, mg | 498.0 | 589.0 | 608.0 | 693.0 | 626.0 | 612.0 | 599.0 | 440.0 | 550.0 | 592.0 | 671.0 |
| Sampling place | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia |
| Sampling date | Aug. 14, 2020 | Sept. 22, 2020 | Sept. 22, 2020 | Sept. 22, 2020 | Aug. 12, 2020 | Sept. 9, 2020 | Sept. 16, 2020 | Aug. 14, 2020 | Sept. 22, 2020 | Sept. 22, 2020 | Sept. 22, 2020 |
| Time postmortem, min | 600 | 600 | 600 | 600 | 600 | 600 | 600 | 600 | 600 | 600 | 600 |