| Property | Value |
|---|---|
| Experiment name | Rats brain |
| Experiment ID | 169 |
| Sample groups | Wistar20days , OXYS20days , Wistar18monats , OXYS18 monats |
| Species | Rat (Rattus norvegicus) |
| Tissues | Brain |
| Diseases | N/A |
| Date of creation | 17:39, Jul 07, 2021 |
| Date of last modification | 17:39, Jul 07, 2021 |
| Author | y.tsentalovich |
| Metabolites / Groups | Wistar20days | OXYS20days | Wistar18monats | OXYS18 monats |
|---|---|---|---|---|
| 3-Hydroxyisovaleric acid | 56.4 ± 5.0 | 35.1 ± 2.5 | 27.5 ± 1.6 | 28.5 ± 0.5 |
| Acetic acid | 338.8 ± 10.7 | 290.9 ± 18.4 | 445.5 ± 56.6 | 470.9 ± 13.3 |
| Acetylcarnitine | 38.5 ± 3.0 | 43.7 ± 7.5 | 29.6 ± 2.2 | 31.0 ± 2.4 |
| Adenosine | 261.2 ± 27.8 | 214.9 ± 14.7 | 783.4 ± 42.2 | 887.3 ± 118.1 |
| ADP | 134.4 ± 4.3 | 143.2 ± 12.1 | 176.6 ± 21.5 | 106.1 ± 15.5 |
| Alanine | 953.2 ± 92.0 | 792.2 ± 41.4 | 799.2 ± 64.9 | 830.9 ± 42.1 |
| Allantoin | 31.6 ± 2.9 | 21.3 ± 3.7 | 6.4 ± 2.1 | 9.1 ± 1.6 |
| alpha-Aminobutyric acid | 20.6 ± 3.7 | 15.7 ± 6.5 | 7.1 ± 1.5 | 7.5 ± 0.7 |
| AMP | 1762.3 ± 92.1 | 1538.6 ± 38.4 | 614.9 ± 75.9 | 553.6 ± 151.3 |
| Ascorbic acid | 1776.9 ± 46.9 | 1754.2 ± 72.8 | 1094.6 ± 93.0 | 1200.3 ± 106.3 |
| Asparagine | 143.8 ± 11.6 | 130.5 ± 18.0 | 114.7 ± 8.1 | 122.4 ± 15.1 |
| Aspartic acid | 3111.2 ± 413.4 | 2776.6 ± 16.2 | 2339.2 ± 125.2 | 2568.6 ± 136.5 |
| ATP | 33.2 ± 8.1 | 46.5 ± 6.0 | 76.6 ± 17.3 | 10.7 ± 2.7 |
| Carnitine | 235.0 ± 4.9 | 218.8 ± 8.6 | 210.6 ± 9.9 | 220.4 ± 11.3 |
| Carnosine | 46.9 ± 2.9 | 33.2 ± 4.3 | 81.0 ± 1.2 | 64.1 ± 3.8 |
| Choline | 139.2 ± 6.5 | 130.5 ± 10.0 | 183.8 ± 22.2 | 180.4 ± 17.0 |
| Creatine | 8341.5 ± 317.8 | 8047.4 ± 345.5 | 8669.0 ± 81.3 | 8402.0 ± 321.5 |
| Cytidine | 58.9 ± 4.1 | 53.1 ± 1.8 | 32.5 ± 5.2 | 27.4 ± 1.2 |
| Formic acid | 613.4 ± 63.2 | 409.3 ± 15.4 | 314.7 ± 21.4 | 344.7 ± 19.4 |
| Fumaric acid | 92.0 ± 9.8 | 76.1 ± 9.1 | 80.0 ± 1.9 | 85.9 ± 7.3 |
| gamma-Aminobutyric acid | 1867.3 ± 126.1 | 2072.5 ± 62.7 | 1991.1 ± 65.2 | 2325.3 ± 138.5 |
| Glutamic acid | 10498.7 ± 453.3 | 10100.7 ± 293.8 | 10302.4 ± 569.8 | 10626.6 ± 541.9 |
| Glutamine | 3412.8 ± 234.0 | 3219.0 ± 180.8 | 4484.4 ± 198.7 | 3983.4 ± 117.5 |
| Glycerol | 278.6 ± 30.1 | 253.4 ± 17.2 | 348.3 ± 12.7 | 380.8 ± 11.8 |
| Glycerophosphocholine | 215.8 ± 29.9 | 252.9 ± 10.6 | 532.9 ± 24.1 | 519.8 ± 14.1 |
| Glycine | 546.2 ± 21.0 | 490.0 ± 15.7 | 856.1 ± 64.3 | 703.8 ± 12.8 |
| GMP | 306.7 ± 29.5 | 292.7 ± 13.6 | 189.5 ± 12.0 | 196.9 ± 31.4 |
| GSH | 732.9 ± 43.8 | 798.6 ± 19.3 | 573.4 ± 37.6 | 602.3 ± 16.4 |
| GSSG | 294.9 ± 11.9 | 307.8 ± 13.3 | 364.5 ± 25.2 | 321.8 ± 24.2 |
| Guanosine | 23.6 ± 3.8 | 19.8 ± 0.2 | 49.0 ± 7.6 | 53.7 ± 12.6 |
| Histidine | 113.9 ± 9.3 | 85.6 ± 7.7 | 60.5 ± 1.4 | 61.7 ± 2.6 |
| Hypotaurine | 477.9 ± 23.2 | 239.1 ± 21.1 | 92.4 ± 7.6 | 46.1 ± 2.5 |
| Hypoxanthine | 100.5 ± 4.7 | 96.2 ± 5.2 | 104.6 ± 6.1 | 121.5 ± 9.9 |
| IMP | 232.1 ± 14.6 | 285.2 ± 37.4 | 230.6 ± 23.1 | 205.0 ± 34.4 |
| Inosine | 212.0 ± 11.7 | 254.5 ± 43.2 | 426.4 ± 40.2 | 478.9 ± 48.2 |
| Isobutyric acid | 9.2 ± 0.5 | 6.4 ± 0.9 | 4.4 ± 0.3 | 5.7 ± 0.6 |
| Isoleucine | 37.7 ± 1.3 | 31.9 ± 3.3 | 35.3 ± 2.0 | 33.3 ± 2.4 |
| Lactic acid | 9591.0 ± 1098.5 | 10530.0 ± 1068.7 | 13846.4 ± 366.6 | 13331.2 ± 554.8 |
| Leucine | 98.4 ± 8.0 | 89.4 ± 8.6 | 77.9 ± 2.9 | 80.5 ± 4.0 |
| myo-Inositol | 4391.3 ± 339.0 | 5163.9 ± 251.6 | 7841.9 ± 450.4 | 7982.3 ± 540.0 |
| N-acetyl-Aspartic acid | 6439.7 ± 433.6 | 5456.7 ± 215.8 | 6012.2 ± 76.0 | 5648.8 ± 165.8 |
| NAD | 104.6 ± 13.3 | 56.7 ± 20.9 | 11.9 ± 4.7 | 3.7 ± 1.7 |
| NADH | 16.3 ± 4.3 | 16.2 ± 2.2 | 17.4 ± 5.9 | 6.1 ± 1.1 |
| Nicotinamide | 172.9 ± 18.7 | 171.8 ± 5.3 | 224.6 ± 11.1 | 246.1 ± 6.8 |
| Pantothenic acid | 16.6 ± 2.0 | 14.1 ± 0.4 | 12.9 ± 0.7 | 12.8 ± 0.4 |
| Phenylalanine | 95.2 ± 5.4 | 69.1 ± 7.6 | 62.5 ± 2.2 | 60.6 ± 4.7 |
| Phosphocholine | 678.3 ± 6.2 | 593.8 ± 25.2 | 493.2 ± 29.1 | 472.7 ± 4.1 |
| Phosphoethanolamine | 1968.7 ± 93.7 | 1742.6 ± 158.1 | 1218.8 ± 44.6 | 1314.9 ± 55.7 |
| Pyruvic acid | 47.4 ± 3.1 | 38.0 ± 3.8 | 27.8 ± 3.2 | 39.3 ± 3.8 |
| scyllo-Inositol | 64.3 ± 2.5 | 105.0 ± 2.1 | 97.7 ± 15.2 | 143.6 ± 4.3 |
| Serine | 1066.1 ± 67.8 | 1102.6 ± 127.5 | 886.7 ± 32.1 | 851.3 ± 52.7 |
| Succinic acid | 367.4 ± 17.0 | 331.0 ± 28.8 | 194.0 ± 39.1 | 102.3 ± 17.2 |
| Taurine | 9487.4 ± 117.7 | 9441.4 ± 588.1 | 5735.5 ± 170.1 | 5332.8 ± 240.0 |
| Threonine | 322.2 ± 23.2 | 357.5 ± 19.6 | 572.4 ± 29.7 | 367.4 ± 13.6 |
| Tryptophan | 100.7 ± 20.9 | 87.1 ± 3.9 | 59.8 ± 4.3 | 72.4 ± 12.3 |
| Tyrosine | 141.2 ± 8.9 | 117.8 ± 0.5 | 59.8 ± 5.6 | 76.3 ± 3.0 |
| Uridine | 128.8 ± 21.2 | 105.6 ± 8.8 | 101.9 ± 4.7 | 100.2 ± 6.4 |
| Valine | 70.2 ± 4.3 | 66.9 ± 4.4 | 74.1 ± 5.5 | 71.8 ± 1.1 |
| Metabolites / Samples | Wistar20daysS1 | Wistar20daysS2 | Wistar20daysS3 | Wistar20daysS4 | Wistar20daysS5 | Wistar20daysS6 | OXYS20daysS1 | OXYS20daysS2 | OXYS20daysS3 | OXYS20daysS4 | OXYS20daysS5 | Wistar18monatsS1 | Wistar18monatsS2 | Wistar18monatsS3 | Wistar18monatsS4 | Wistar18monatsS5 | Wistar18monatsS6 | OXYS18 monatsS1 | OXYS18 monatsS2 | OXYS18 monatsS3 | OXYS18 monatsS4 | OXYS18 monatsS5 | OXYS18 monatsS6 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 3-Hydroxyisovaleric acid | 88.6 | 42.9 | 55.4 | 46.5 | 47.5 | 57.2 | 42.6 | 29.5 | 31.1 | 36.1 | 36.0 | 26.3 | 30.4 | 26.6 | 27.1 | 31.9 | 23.0 | 27.7 | 36.1 | 26.5 | 25.9 | 27.4 | 27.3 |
| Acetic acid | 410.7 | 315.7 | 337.3 | 305.4 | 339.8 | 323.9 | 287.6 | 225.4 | 271.3 | 308.1 | 361.8 | 541.7 | 427.5 | 333.9 | 503.3 | 374.2 | 492.5 | 448.8 | 449.2 | 480.8 | 444.3 | 542.7 | 459.4 |
| Acetylcarnitine | 47.8 | 42.9 | 35.9 | 37.1 | 35.2 | 32.0 | 52.8 | 31.4 | 44.7 | 37.4 | 52.3 | 24.4 | 29.4 | 29.3 | 33.5 | 33.4 | 27.6 | 39.4 | 34.2 | 30.3 | 21.3 | 32.4 | 28.6 |
| Adenosine | 314.7 | 231.7 | 301.2 | 258.8 | 215.7 | 245.0 | 219.2 | 243.3 | 224.6 | 192.4 | 195.2 | 824.0 | 715.1 | 803.6 | 792.8 | 876.5 | 688.1 | 763.5 | 727.1 | 1063.7 | 880.3 | 1061.1 | 828.3 |
| ADP | 129.0 | 138.5 | 132.4 | 138.4 | 158.5 | 109.4 | 122.6 | 129.9 | 154.2 | 155.6 | 153.8 | 187.9 | 202.9 | 153.1 | 226.6 | 165.7 | 123.4 | 88.8 | 68.2 | 94.1 | 100.5 | 128.0 | 157.1 |
| Alanine | 1111.7 | 1076.4 | 836.9 | 945.9 | 820.0 | 928.2 | 806.8 | 740.3 | 742.9 | 825.7 | 845.3 | 879.9 | 837.2 | 771.7 | 728.6 | 920.5 | 657.3 | 781.8 | 774.1 | 805.2 | 917.2 | 890.0 | 817.3 |
| Allantoin | 30.4 | 27.6 | 36.5 | 28.2 | 35.7 | 31.4 | 18.4 | 15.2 | 20.3 | 26.6 | 25.9 | 6.3 | 11.2 | 9.7 | 6.6 | 4.1 | 0.6 | 9.6 | 9.2 | 4.2 | 12.4 | 7.6 | 11.6 |
| alpha-Aminobutyric acid | 25.6 | 16.3 | 14.0 | 16.8 | 32.5 | 18.4 | 17.4 | 9.1 | 7.1 | 22.1 | 22.7 | 7.4 | 9.7 | 8.9 | 4.6 | 5.2 | 6.9 | 6.3 | 6.0 | 7.6 | 14.7 | 3.0 | 7.2 |
| AMP | 1931.8 | 1784.5 | 1974.1 | 1689.2 | 1793.2 | 1400.8 | 1644.9 | 1497.0 | 1429.6 | 1573.8 | 1547.6 | 670.6 | 796.5 | 494.7 | 596.4 | 672.4 | 458.8 | 564.3 | 363.5 | 321.9 | 754.0 | 525.4 | 792.6 |
| Ascorbic acid | 1868.1 | 1806.6 | 1970.9 | 1803.6 | 1744.0 | 1468.5 | 1812.0 | 1666.3 | 1653.0 | 1807.8 | 1831.7 | 1218.2 | 1197.9 | 1009.2 | 1080.4 | 1256.5 | 805.6 | 1155.0 | 1016.2 | 1087.0 | 1324.2 | 1294.0 | 1325.1 |
| Asparagine | 133.4 | 147.8 | 158.0 | 131.8 | 131.8 | 160.3 | 132.1 | 109.4 | 109.5 | 156.0 | 145.5 | 124.6 | 131.3 | 110.8 | 117.0 | 105.0 | 99.5 | 129.9 | 144.9 | 131.1 | 139.6 | 99.8 | 88.8 |
| Aspartic acid | 3738.8 | 2902.2 | 3374.9 | 2635.8 | 3580.7 | 2434.5 | 2963.1 | 2500.6 | 2811.2 | 2788.0 | 2820.3 | 2549.9 | 2280.4 | 2197.0 | 2378.1 | 2498.3 | 2131.8 | 2587.8 | 2107.7 | 2432.3 | 2550.0 | 2783.8 | 2949.9 |
| ATP | 24.6 | 43.6 | 27.7 | 49.5 | 35.1 | 18.8 | 58.4 | 55.9 | 43.8 | 51.0 | 23.2 | 99.4 | 83.4 | 79.9 | 54.5 | 114.7 | 27.9 | 6.9 | 4.4 | 13.9 | 12.0 | 11.3 | 15.7 |
| Carnitine | 254.1 | 228.7 | 241.6 | 239.2 | 239.9 | 206.5 | 232.8 | 201.9 | 208.6 | 225.8 | 224.8 | 201.4 | 210.3 | 212.1 | 227.2 | 249.4 | 163.1 | 223.9 | 213.3 | 206.1 | 245.6 | 201.0 | 232.7 |
| Carnosine | 65.9 | 48.3 | 41.3 | 48.6 | 47.3 | 29.7 | 46.4 | 38.4 | 31.0 | 20.3 | 29.9 | 84.4 | 87.5 | 84.6 | 95.3 | 84.3 | 50.1 | 68.0 | 65.5 | 72.3 | 61.9 | 58.1 | 58.9 |
| Choline | 178.0 | 137.4 | 125.1 | 114.9 | 137.5 | 142.4 | 120.9 | 110.7 | 141.0 | 127.5 | 152.4 | 156.6 | 157.5 | 221.2 | 180.2 | 173.1 | 214.4 | 198.7 | 232.8 | 180.5 | 157.8 | 145.5 | 167.4 |
| Creatine | 9470.4 | 8742.6 | 8342.4 | 7909.3 | 8299.9 | 7284.7 | 8617.3 | 7655.8 | 7550.2 | 8066.8 | 8346.9 | 8867.0 | 8742.9 | 8818.8 | 8943.8 | 9369.9 | 7271.6 | 8275.4 | 7740.5 | 8029.9 | 8788.2 | 8572.5 | 9005.5 |
| Cytidine | 64.1 | 66.6 | 53.4 | 58.5 | 59.5 | 51.0 | 53.7 | 56.1 | 55.8 | 52.2 | 47.5 | 31.3 | 38.4 | 38.8 | 37.2 | 26.6 | 22.5 | 16.3 | 28.6 | 26.5 | 37.0 | 26.9 | 29.3 |
| Formic acid | 880.1 | 466.7 | 566.8 | 501.4 | 655.3 | 610.3 | 500.7 | 385.1 | 342.8 | 402.1 | 416.0 | 295.8 | 332.7 | 329.5 | 239.6 | 403.6 | 287.0 | 304.1 | 333.3 | 390.3 | 323.8 | 371.6 | 344.8 |
| Fumaric acid | 110.6 | 105.0 | 93.1 | 83.9 | 82.0 | 77.7 | 69.3 | 59.7 | 72.3 | 87.5 | 91.8 | 88.8 | 78.8 | 77.6 | 71.9 | 82.0 | 80.8 | 79.3 | 80.0 | 95.3 | 102.2 | 90.3 | 68.3 |
| gamma-Aminobutyric acid | 1928.6 | 2214.3 | 1631.4 | 1950.2 | 1603.7 | 1876.0 | 2224.6 | 2004.3 | 1931.5 | 2072.2 | 2129.8 | 1878.7 | 2031.4 | 1959.7 | 2023.3 | 2256.3 | 1797.1 | 2310.4 | 2493.2 | 2236.0 | 2623.2 | 2140.4 | 2148.6 |
| Glutamic acid | 11578.1 | 11085.9 | 10811.9 | 9922.0 | 10946.4 | 8647.6 | 10220.3 | 9745.9 | 9705.9 | 10497.9 | 10333.6 | 11259.0 | 10639.2 | 10081.0 | 9925.7 | 12044.0 | 7865.4 | 9974.3 | 9475.3 | 10390.1 | 11718.0 | 10978.9 | 11223.1 |
| Glutamine | 3696.4 | 3990.0 | 3297.0 | 3148.6 | 3525.3 | 2819.2 | 3478.8 | 3153.6 | 2944.2 | 3440.1 | 3078.4 | 4698.9 | 4446.8 | 4175.6 | 4427.6 | 5551.0 | 3606.4 | 3940.1 | 3829.8 | 3820.2 | 4300.4 | 3885.0 | 4124.8 |
| Glycerol | 306.4 | 323.4 | 254.8 | 244.4 | 235.3 | 307.4 | 231.6 | 243.8 | 233.8 | 268.2 | 289.5 | 350.6 | 334.8 | 386.1 | 351.0 | 368.5 | 298.9 | 373.9 | 373.8 | 420.4 | 401.6 | 385.2 | 330.1 |
| Glycerophosphocholine | 226.7 | 166.9 | 222.2 | 270.3 | 245.0 | 163.7 | 296.1 | 255.5 | 256.0 | 234.8 | 222.2 | 570.7 | 523.0 | 521.1 | 600.9 | 567.3 | 414.6 | 506.3 | 528.7 | 539.5 | 508.8 | 498.0 | 537.4 |
| Glycine | 601.5 | 551.0 | 523.3 | 570.7 | 505.3 | 525.2 | 499.9 | 434.9 | 472.4 | 503.7 | 538.8 | 851.0 | 771.1 | 921.7 | 913.6 | 931.0 | 748.6 | 684.4 | 677.0 | 740.8 | 714.1 | 696.3 | 710.1 |
| GMP | 366.3 | 322.8 | 264.1 | 335.4 | 300.9 | 250.4 | 307.3 | 289.9 | 275.8 | 280.2 | 310.0 | 206.4 | 218.5 | 176.9 | 187.7 | 195.5 | 151.8 | 194.6 | 157.8 | 153.1 | 240.0 | 189.7 | 246.5 |
| GSH | 710.7 | 757.7 | 768.7 | 667.6 | 877.7 | 615.2 | 754.8 | 758.1 | 794.1 | 755.4 | 930.5 | 504.4 | 692.5 | 566.7 | 544.8 | 612.4 | 519.4 | 590.7 | 607.2 | 543.7 | 721.2 | 586.2 | 565.1 |
| GSSG | 285.2 | 334.8 | 287.5 | 310.0 | 308.7 | 243.0 | 291.2 | 269.1 | 317.7 | 355.8 | 305.2 | 407.9 | 343.5 | 365.1 | 373.4 | 458.1 | 239.0 | 347.2 | 283.0 | 345.0 | 335.9 | 276.3 | 343.5 |
| Guanosine | 28.1 | 19.1 | 26.3 | 17.6 | 28.0 | 22.9 | 20.1 | 23.5 | 20.5 | 20.1 | 14.6 | 54.5 | 22.6 | 58.2 | 72.2 | 45.8 | 40.8 | 36.6 | 46.9 | 79.6 | 38.2 | 70.8 | 50.0 |
| Histidine | 119.1 | 112.1 | 159.1 | 95.4 | 115.5 | 82.2 | 80.4 | 72.3 | 79.4 | 94.7 | 101.2 | 59.6 | 62.8 | 61.7 | 59.9 | 72.2 | 47.1 | 59.8 | 65.1 | 58.7 | 61.8 | 57.3 | 67.3 |
| Hypotaurine | 483.7 | 593.0 | 480.6 | 424.8 | 399.8 | 485.6 | 266.9 | 261.4 | 231.8 | 216.1 | 219.1 | 86.2 | 102.3 | 113.2 | 77.2 | 83.9 | 91.5 | 40.0 | 45.6 | 43.0 | 43.7 | 55.2 | 49.2 |
| Hypoxanthine | 130.4 | 102.3 | 91.1 | 95.2 | 98.7 | 85.2 | 85.1 | 91.8 | 91.6 | 101.9 | 110.5 | 96.3 | 94.1 | 122.5 | 111.6 | 103.1 | 100.3 | 119.8 | 149.0 | 132.3 | 117.6 | 103.7 | 106.6 |
| IMP | 232.0 | 239.2 | 211.4 | 185.3 | 317.4 | 207.2 | 256.4 | 234.3 | 253.0 | 327.8 | 354.4 | 294.0 | 214.3 | 209.2 | 185.8 | 269.7 | 210.6 | 247.4 | 203.1 | 130.7 | 209.6 | 157.9 | 281.3 |
| Inosine | 232.1 | 229.3 | 203.7 | 186.7 | 217.4 | 202.7 | 211.5 | 183.3 | 247.0 | 297.9 | 332.6 | 396.8 | 310.6 | 498.9 | 525.6 | 405.7 | 420.8 | 490.0 | 656.2 | 514.4 | 438.8 | 403.1 | 371.0 |
| Isobutyric acid | 10.1 | 10.5 | 8.6 | 9.1 | 9.1 | 7.9 | 8.0 | 4.9 | 5.4 | 6.9 | 7.1 | 3.4 | 4.5 | 3.9 | 4.3 | 6.7 | 3.7 | 4.7 | 4.9 | 6.1 | 4.6 | 8.4 | 5.3 |
| Isoleucine | 36.2 | 45.7 | 38.8 | 35.3 | 34.3 | 35.9 | 35.1 | 28.4 | 27.1 | 31.7 | 37.1 | 39.1 | 34.7 | 34.1 | 38.3 | 38.4 | 27.4 | 30.1 | 30.2 | 32.7 | 40.5 | 35.7 | 30.4 |
| Lactic acid | 11238.1 | 11424.3 | 8456.3 | 9299.6 | 7385.4 | 9742.5 | 11001.6 | 9278.2 | 9276.8 | 11415.5 | 11677.7 | 14324.4 | 13977.1 | 14368.6 | 13506.7 | 15207.3 | 11694.3 | 12608.3 | 12393.0 | 12974.0 | 14557.2 | 13891.2 | 13563.8 |
| Leucine | 108.9 | 94.2 | 120.0 | 89.9 | 89.0 | 88.1 | 95.8 | 76.3 | 97.3 | 80.1 | 97.6 | 76.8 | 76.6 | 88.0 | 84.3 | 77.2 | 64.6 | 74.2 | 80.3 | 74.5 | 84.8 | 81.3 | 88.2 |
| myo-Inositol | 4736.0 | 5407.8 | 4004.1 | 4427.3 | 3799.2 | 3973.2 | 5588.8 | 5327.9 | 5277.9 | 4824.7 | 4800.2 | 8600.7 | 8291.8 | 8086.2 | 7237.8 | 8370.4 | 6464.6 | 7353.4 | 7266.1 | 7608.9 | 8532.1 | 8392.7 | 8740.9 |
| N-acetyl-Aspartic acid | 7626.6 | 6246.4 | 6809.3 | 5837.6 | 6800.1 | 5318.1 | 5887.2 | 5247.6 | 5062.5 | 5406.9 | 5679.1 | 6206.4 | 6051.3 | 6015.2 | 6085.8 | 6783.5 | 4931.1 | 5547.1 | 5232.4 | 5515.4 | 5891.9 | 5743.6 | 5962.1 |
| NAD | 111.7 | 93.3 | 151.8 | 115.8 | 127.4 | 27.8 | 78.7 | 77.8 | 66.3 | 35.9 | 24.7 | 9.3 | 17.9 | 7.1 | 17.9 | 14.4 | 4.6 | 1.9 | 7.3 | 2.9 | 6.2 | 1.6 | 2.2 |
| NADH | 23.6 | 13.5 | 22.1 | 22.5 | 14.9 | 1.4 | 30.3 | 17.5 | 6.7 | 13.5 | 13.1 | 24.3 | 27.3 | 18.7 | 7.1 | 18.6 | 8.6 | 6.5 | 4.5 | 10.7 | 7.0 | 5.2 | 2.5 |
| Nicotinamide | 195.8 | 147.8 | 173.3 | 126.8 | 179.2 | 214.6 | 166.6 | 138.2 | 164.3 | 174.9 | 214.8 | 239.2 | 219.6 | 210.4 | 222.1 | 262.6 | 193.6 | 241.8 | 230.5 | 252.6 | 255.0 | 240.5 | 256.2 |
| Pantothenic acid | 19.8 | 12.3 | 18.3 | 19.0 | 15.7 | 14.6 | 14.5 | 13.7 | 13.7 | 16.4 | 12.4 | 13.3 | 13.6 | 12.7 | 15.4 | 12.0 | 10.6 | 12.3 | 14.0 | 12.4 | 13.3 | 12.1 | 12.8 |
| Phenylalanine | 100.8 | 87.6 | 93.8 | 89.6 | 111.6 | 87.9 | 54.4 | 64.7 | 78.1 | 62.9 | 85.5 | 58.3 | 57.0 | 64.1 | 72.7 | 61.7 | 61.5 | 54.9 | 64.0 | 65.0 | 56.7 | 50.5 | 72.5 |
| Phosphocholine | 690.9 | 724.8 | 679.2 | 676.1 | 684.3 | 614.5 | 594.9 | 515.7 | 583.1 | 633.5 | 642.0 | 506.6 | 457.3 | 533.7 | 501.0 | 533.1 | 427.6 | 474.9 | 478.8 | 458.5 | 484.4 | 469.6 | 469.9 |
| Phosphoethanolamine | 2184.5 | 1902.4 | 2142.9 | 1923.4 | 1951.5 | 1707.3 | 1662.7 | 1571.4 | 1592.3 | 1977.9 | 1908.4 | 1235.7 | 1179.1 | 1287.6 | 1204.3 | 1450.1 | 956.2 | 1261.5 | 1193.6 | 1236.0 | 1538.9 | 1377.8 | 1281.8 |
| Pyruvic acid | 56.8 | 46.2 | 51.8 | 45.2 | 43.8 | 40.7 | 36.0 | 32.7 | 33.4 | 47.0 | 41.0 | 33.4 | 28.9 | 30.7 | 23.4 | 31.2 | 19.2 | 42.8 | 55.6 | 41.8 | 35.3 | 34.8 | 25.6 |
| scyllo-Inositol | 77.5 | 67.1 | 60.6 | 61.5 | 61.3 | 57.7 | 105.4 | 92.9 | 105.8 | 111.1 | 109.6 | 121.5 | 92.3 | 82.1 | 89.1 | 128.7 | 72.5 | 142.7 | 138.5 | 148.1 | 137.5 | 156.8 | 137.9 |
| Serine | 1230.2 | 1148.8 | 1096.7 | 1012.0 | 912.5 | 996.1 | 1008.0 | 983.4 | 979.7 | 1238.3 | 1303.7 | 1038.5 | 865.1 | 926.5 | 852.6 | 900.3 | 737.0 | 775.1 | 779.1 | 845.1 | 902.0 | 908.6 | 898.2 |
| Succinic acid | 396.7 | 386.5 | 362.9 | 415.9 | 359.2 | 283.3 | 374.5 | 366.3 | 333.7 | 271.6 | 308.8 | 223.0 | 260.0 | 139.3 | 234.5 | 239.8 | 67.3 | 95.0 | 37.6 | 83.8 | 123.6 | 113.6 | 160.2 |
| Taurine | 9665.8 | 10344.0 | 9791.5 | 9546.4 | 9517.5 | 8059.1 | 9300.8 | 8901.7 | 8770.9 | 10077.9 | 10155.9 | 6047.4 | 6224.8 | 5665.6 | 5944.5 | 5728.6 | 4801.9 | 5496.3 | 4943.0 | 5395.9 | 5776.7 | 4835.2 | 5549.5 |
| Threonine | 301.3 | 334.7 | 406.9 | 332.7 | 283.2 | 274.4 | 348.0 | 273.0 | 387.1 | 411.8 | 367.6 | 613.7 | 684.2 | 557.1 | 546.2 | 592.3 | 441.1 | 329.6 | 399.6 | 388.0 | 366.5 | 352.3 | 368.1 |
| Tryptophan | 122.1 | 78.8 | 137.8 | 113.1 | 77.8 | 74.8 | 85.7 | 98.8 | 67.8 | 89.4 | 93.6 | 55.0 | 56.3 | 65.9 | 46.3 | 77.7 | 57.8 | 110.5 | 68.5 | 91.2 | 60.5 | 62.0 | 41.9 |
| Tyrosine | 133.6 | 131.0 | 134.8 | 154.4 | 172.0 | 121.7 | 107.0 | 122.2 | 119.4 | 119.7 | 120.5 | 51.1 | 52.3 | 59.4 | 66.4 | 73.2 | 56.5 | 71.7 | 72.4 | 78.2 | 88.6 | 76.9 | 70.2 |
| Uridine | 155.8 | 139.8 | 155.2 | 114.9 | 106.9 | 100.2 | 105.8 | 94.9 | 96.3 | 113.9 | 117.0 | 116.4 | 99.7 | 97.6 | 110.0 | 100.4 | 87.2 | 85.4 | 112.4 | 107.5 | 94.0 | 106.4 | 95.4 |
| Valine | 65.4 | 76.6 | 74.5 | 75.3 | 70.1 | 59.3 | 66.6 | 61.1 | 53.2 | 70.0 | 83.8 | 81.1 | 79.9 | 72.3 | 68.5 | 80.6 | 62.0 | 65.0 | 71.5 | 73.8 | 75.7 | 73.1 | 71.7 |
| Properties / Samples | Wistar20daysS1 | Wistar20daysS2 | Wistar20daysS3 | Wistar20daysS4 | Wistar20daysS5 | Wistar20daysS6 | OXYS20daysS1 | OXYS20daysS2 | OXYS20daysS3 | OXYS20daysS4 | OXYS20daysS5 | Wistar18monatsS1 | Wistar18monatsS2 | Wistar18monatsS3 | Wistar18monatsS4 | Wistar18monatsS5 | Wistar18monatsS6 | OXYS18 monatsS1 | OXYS18 monatsS2 | OXYS18 monatsS3 | OXYS18 monatsS4 | OXYS18 monatsS5 | OXYS18 monatsS6 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Group | Wistar20days | Wistar20days | Wistar20days | Wistar20days | Wistar20days | Wistar20days | OXYS20days | OXYS20days | OXYS20days | OXYS20days | OXYS20days | Wistar18monats | Wistar18monats | Wistar18monats | Wistar18monats | Wistar18monats | Wistar18monats | OXYS18 monats | OXYS18 monats | OXYS18 monats | OXYS18 monats | OXYS18 monats | OXYS18 monats |
| Description | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Species | Rat (Rattus norve… | Rat (Rattus norve… | Rat (Rattus norve… | Rat (Rattus norve… | Rat (Rattus norve… | Rat (Rattus norve… | Rat (Rattus norve… | Rat (Rattus norve… | Rat (Rattus norve… | Rat (Rattus norve… | Rat (Rattus norve… | Rat (Rattus norve… | Rat (Rattus norve… | Rat (Rattus norve… | Rat (Rattus norve… | Rat (Rattus norve… | Rat (Rattus norve… | Rat (Rattus norve… | Rat (Rattus norve… | Rat (Rattus norve… | Rat (Rattus norve… | Rat (Rattus norve… | Rat (Rattus norve… |
| Tissue | Brain | Brain | Brain | Brain | Brain | Brain | Brain | Brain | Brain | Brain | Brain | Brain | Brain | Brain | Brain | Brain | Brain | Brain | Brain | Brain | Brain | Brain | Brain |
| Diseases | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Gender | male | male | male | male | male | male | male | male | male | male | male | male | male | male | male | male | male | male | male | male | male | male | male |
| Origin | laboratory | laboratory | laboratory | laboratory | laboratory | laboratory | laboratory | laboratory | laboratory | laboratory | laboratory | laboratory | laboratory | laboratory | laboratory | laboratory | laboratory | laboratory | laboratory | laboratory | laboratory | laboratory | laboratory |
| Sample weight, mg | 41.3 | 82.7 | 58.8 | 83.3 | 68.8 | 57.3 | 80.4 | 112.9 | 102.0 | 93.7 | 89.8 | 141.2 | 122.2 | 124.4 | 141.1 | 121.9 | 152.1 | 118.1 | 97.3 | 138.8 | 126.2 | 139.4 | 144.6 |
| Sampling place | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | N/A | N/A | N/A | N/A | N/A | N/A |
| Sampling date | April 5, 2021 | April 5, 2021 | April 5, 2021 | April 5, 2021 | April 5, 2021 | April 5, 2021 | April 5, 2021 | April 5, 2021 | April 5, 2021 | April 5, 2021 | April 5, 2021 | Aug. 18, 2017 | Aug. 18, 2017 | Aug. 18, 2017 | Aug. 18, 2017 | Aug. 18, 2017 | Aug. 18, 2017 | Aug. 18, 2017 | Aug. 18, 2017 | Aug. 18, 2017 | Aug. 18, 2017 | Aug. 18, 2017 | Aug. 18, 2017 |
| Age, months | 0.7 | 0.7 | 0.7 | 0.7 | 0.7 | 0.7 | 0.7 | 0.7 | 0.7 | 0.7 | 0.7 | 18 | 18 | 18 | 18 | 18 | 18 | 18 | 18 | 18 | 18 | 18 | 18 |
| Time postmortem, min | 10 | 10 | 10 | 10 | 10 | 10 | 10 | 10 | 10 | 10 | 10 | 10 | 10 | 10 | 10 | 10 | 10 | 10 | 10 | 10 | 10 | 10 | 10 |