| Property | Value |
|---|---|
| Experiment name | Rat brain 3 months |
| Experiment ID | 267 |
| Sample groups | OXYS rat brain 3m, Wistar brain 3m |
| Species | Rat (Rattus norvegicus) |
| Tissues | Brain |
| Diseases | N/A |
| Date of creation | 15:26, Jun 01, 2023 |
| Date of last modification | 09:41, Sep 07, 2023 |
| Author | y.tsentalovich |
| Metabolites / Groups | OXYS rat brain 3m | Wistar brain 3m |
|---|---|---|
| 2-Aminobutyric acid | 13.0 ± 1.7 | 12.9 ± 0.5 |
| 3-Hydroxyisovaleric acid | 7.0 ± 2.8 | 8.6 ± 3.1 |
| 4-Aminobutyric acid | 2721.9 ± 280.4 | 2472.4 ± 316.8 |
| Acetic acid | 432.6 ± 46.8 | 406.5 ± 41.5 |
| Acetylcarnitine | 20.2 ± 3.1 | 24.1 ± 6.3 |
| Adenosine | 976.9 ± 135.9 | 961.2 ± 93.7 |
| ADP | 634.4 ± 139.0 | 520.7 ± 117.9 |
| Alanine | 879.8 ± 78.3 | 896.0 ± 73.4 |
| Allantoin | 113.1 ± 19.8 | 191.8 ± 19.8 |
| AMP | 580.8 ± 106.4 | 640.2 ± 152.8 |
| Ascorbic acid | 1315.9 ± 90.5 | 1225.9 ± 96.8 |
| Asparagine | 124.2 ± 10.3 | 121.1 ± 12.4 |
| Aspartic acid | 3020.7 ± 191.8 | 2721.6 ± 248.3 |
| ATP | 126.3 ± 15.1 | 129.5 ± 22.1 |
| Carnitine | 218.1 ± 19.0 | 213.6 ± 15.4 |
| Carnosine | 6.9 ± 2.1 | 6.0 ± 3.6 |
| Choline | 267.8 ± 47.8 | 274.4 ± 45.5 |
| Creatine | 9413.1 ± 760.4 | 9299.4 ± 656.6 |
| Cytidine | 6.6 ± 4.0 | 9.4 ± 2.4 |
| Formic acid | 18.6 ± 10.0 | 26.3 ± 13.0 |
| Fumaric acid | 80.5 ± 11.2 | 75.8 ± 9.5 |
| Glutamic acid | 11922.8 ± 950.1 | 11607.6 ± 601.7 |
| Glutamine | 4647.4 ± 297.7 | 4175.6 ± 343.2 |
| Glycerol | 438.9 ± 68.6 | 451.9 ± 18.4 |
| Glycerophosphocholine | 432.9 ± 20.4 | 386.9 ± 51.4 |
| Glycine | 859.7 ± 79.8 | 977.1 ± 69.3 |
| GMP | 222.4 ± 30.9 | 207.0 ± 23.3 |
| GSH | 533.3 ± 83.5 | 505.0 ± 58.1 |
| GSSG | 332.6 ± 36.2 | 314.2 ± 52.0 |
| Guanosine | 39.6 ± 9.2 | 39.1 ± 9.4 |
| Histidine | 58.4 ± 5.7 | 66.7 ± 10.8 |
| Hypotaurine | 31.3 ± 3.3 | 29.9 ± 0.7 |
| Hypoxanthine | 131.8 ± 24.6 | 151.0 ± 20.9 |
| IMP | 32.9 ± 6.7 | 36.7 ± 12.4 |
| Inosine | 337.5 ± 79.6 | 309.8 ± 86.5 |
| Isobutyric acid | 4.9 ± 0.9 | 5.6 ± 1.1 |
| Isoleucine | 41.7 ± 2.9 | 44.9 ± 5.4 |
| Lactic acid | 13066.9 ± 962.0 | 13339.3 ± 591.5 |
| Leucine | 96.0 ± 9.4 | 106.4 ± 14.0 |
| myo-Inositol | 8273.7 ± 687.1 | 8128.6 ± 516.5 |
| N-acetylaspartic acid | 6417.8 ± 490.0 | 6664.7 ± 565.3 |
| NAD | 245.5 ± 23.1 | 240.8 ± 20.2 |
| NADH | 4.6 ± 2.9 | 10.9 ± 2.4 |
| Nicotinamide | 381.6 ± 72.9 | 397.5 ± 80.1 |
| Pantothenic acid | 48.9 ± 6.8 | 60.6 ± 16.6 |
| Phenylalanine | 64.2 ± 12.7 | 71.5 ± 14.9 |
| Phosphocholine | 554.3 ± 54.2 | 586.5 ± 32.6 |
| Phosphoethanolamine | 1372.8 ± 121.9 | 1287.7 ± 119.8 |
| Pyruvic acid | 38.8 ± 8.9 | 35.4 ± 1.8 |
| scyllo-Inositol | 152.9 ± 16.4 | 110.1 ± 12.2 |
| Serine | 963.6 ± 68.2 | 949.7 ± 102.2 |
| Succinic acid | 196.8 ± 65.3 | 233.5 ± 65.5 |
| Taurine | 6255.5 ± 532.1 | 6378.7 ± 506.2 |
| Threonine | 404.1 ± 79.1 | 392.2 ± 63.5 |
| Tryptophan | 39.6 ± 9.6 | 42.0 ± 4.6 |
| Tyrosine | 70.9 ± 10.7 | 71.8 ± 8.6 |
| Uridine | 115.1 ± 10.8 | 132.7 ± 11.1 |
| UTP | 178.4 ± 18.1 | 152.1 ± 9.7 |
| Valine | 95.8 ± 6.9 | 103.8 ± 10.0 |
| Metabolites / Samples | OXYS3monthsS1 | OXYS3monthsS2 | OXYS3monthsS3 | OXYS3monthsS4 | OXYS3monthsS5 | OXYS3monthsS6 | Wistar3monthsS1 | Wistar3monthsS2 | Wistar3monthsS3 | Wistar3monthsS4 | Wistar3monthsS5 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 2-Aminobutyric acid | 14.3 | 11.2 | 10.7 | 13.8 | 13.0 | 15.0 | 13.2 | 12.2 | 13.3 | 12.5 | 13.4 |
| 3-Hydroxyisovaleric acid | 4.4 | 9.6 | 9.8 | 7.8 | 2.9 | 7.4 | 8.6 | 10.4 | 12.1 | 4.0 | 8.0 |
| 4-Aminobutyric acid | 3012.3 | 2629.2 | 2214.3 | 2892.6 | 2748.4 | 2834.7 | 2243.4 | 2074.3 | 2778.1 | 2482.3 | 2783.9 |
| Acetic acid | 463.9 | 460.7 | 340.7 | 444.4 | 429.3 | 456.7 | 445.3 | 373.9 | 417.9 | 352.8 | 442.7 |
| Acetylcarnitine | 20.7 | 18.7 | 20.3 | 25.8 | 16.7 | 19.2 | 31.7 | 14.5 | 26.9 | 24.9 | 22.6 |
| Adenosine | 1015.3 | 1069.0 | 710.2 | 1044.6 | 964.5 | 1057.7 | 1115.8 | 940.8 | 954.9 | 861.3 | 933.2 |
| ADP | 770.6 | 495.4 | 730.0 | 736.4 | 637.2 | 436.6 | 707.6 | 484.9 | 483.4 | 539.8 | 387.8 |
| Alanine | 967.3 | 859.3 | 742.1 | 927.9 | 913.8 | 868.6 | 890.9 | 800.8 | 953.2 | 853.1 | 981.8 |
| Allantoin | 137.5 | 130.6 | 90.1 | 108.4 | 120.2 | 92.0 | 197.8 | 157.7 | 207.0 | 203.6 | 192.7 |
| AMP | 522.2 | 632.5 | 425.1 | 537.5 | 643.7 | 723.6 | 448.6 | 554.6 | 634.7 | 712.8 | 850.2 |
| Ascorbic acid | 1446.0 | 1268.5 | 1189.9 | 1360.5 | 1359.4 | 1271.2 | 1340.7 | 1087.5 | 1289.3 | 1219.3 | 1192.7 |
| Asparagine | 115.0 | 122.2 | 112.0 | 130.1 | 140 | 125.8 | 109.6 | 117.9 | 141.9 | 121.1 | 115.2 |
| Aspartic acid | 3183.2 | 2797.5 | 2791.7 | 3044.8 | 3055.1 | 3251.9 | 2868.9 | 2367.6 | 2976.1 | 2567.8 | 2827.6 |
| ATP | 120.7 | 152.5 | 117.2 | 111.8 | 120.0 | 135.4 | 122.3 | 95.4 | 153.8 | 139.7 | 136.2 |
| Carnitine | 245.2 | 215.7 | 188.5 | 227.9 | 221.9 | 209.3 | 225.4 | 189.5 | 228.4 | 214.2 | 210.5 |
| Carnosine | 8.0 | 6.2 | 6.8 | 3.3 | 9.5 | 7.6 | 5.2 | 2.9 | 8.3 | 2.5 | 11 |
| Choline | 266.3 | 267.8 | 178.6 | 287.3 | 286.7 | 320.0 | 249.9 | 206.2 | 312.8 | 295.2 | 307.9 |
| Creatine | 10369.7 | 9253.2 | 8085.1 | 9822.3 | 9551.9 | 9396.3 | 9969.6 | 8226.7 | 9520.7 | 9217.9 | 9562.0 |
| Cytidine | 9.1 | 12.9 | 2.4 | 7.1 | 2.7 | 5.2 | 12.8 | 9.4 | 6.5 | 10.4 | 7.9 |
| Formic acid | 5.8 | 32.7 | 17.3 | 12.8 | 15.1 | 28.0 | 12.1 | 13.2 | 41.0 | 31.5 | 33.8 |
| Fumaric acid | 80 | 78.8 | 62.9 | 87.4 | 77.3 | 96.6 | 84.0 | 65.5 | 76.7 | 66.7 | 86.1 |
| Glutamic acid | 12878.4 | 11464.3 | 10355.1 | 12850.8 | 11819.7 | 12168.3 | 12116.5 | 10739.9 | 12148.8 | 11264.8 | 11768.1 |
| Glutamine | 4972.0 | 4663.7 | 4126.1 | 4871.7 | 4710.1 | 4540.7 | 4124.2 | 3796.7 | 4622.9 | 3917.4 | 4416.8 |
| Glycerol | 444.1 | 388.8 | 339.2 | 535.7 | 479.5 | 445.8 | 442.7 | 442.5 | 435.1 | 458.2 | 481.2 |
| Glycerophosphocholine | 466.2 | 411.5 | 433.1 | 434.9 | 440.4 | 411.5 | 402.1 | 322.1 | 454.8 | 351.7 | 403.7 |
| Glycine | 873.4 | 867.2 | 703.8 | 921.1 | 876.8 | 916.1 | 992.2 | 891.7 | 1044.9 | 918.7 | 1037.9 |
| GMP | 267.2 | 189.9 | 207.7 | 249.7 | 224.5 | 195.3 | 232.8 | 173.1 | 211.9 | 221.4 | 195.6 |
| GSH | 676.1 | 469.1 | 491.3 | 587.4 | 515.7 | 460.2 | 554.0 | 459.2 | 579.1 | 450.2 | 482.4 |
| GSSG | 358.6 | 306.3 | 298.9 | 390.1 | 335.9 | 305.8 | 247.1 | 299.4 | 293.7 | 351.3 | 379.6 |
| Guanosine | 39.7 | 45.9 | 31.6 | 30.9 | 35.0 | 54.7 | 40.6 | 35.4 | 35.5 | 29.5 | 54.3 |
| Histidine | 64.5 | 63.5 | 55.5 | 59.1 | 48.8 | 59.2 | 75.9 | 50.4 | 74.4 | 61.1 | 71.6 |
| Hypotaurine | 34.0 | 31.3 | 26.2 | 35.7 | 30.6 | 29.9 | 29.0 | 29.9 | 30.2 | 30.9 | 29.7 |
| Hypoxanthine | 126.8 | 124.4 | 89.8 | 145.1 | 143.9 | 161.0 | 126.0 | 136.0 | 157.8 | 155.5 | 179.9 |
| IMP | 42.2 | 23.9 | 30.7 | 38.9 | 32.8 | 29.2 | 31.8 | 27.5 | 32.1 | 33.5 | 58.6 |
| Inosine | 476.7 | 249.1 | 352 | 334.2 | 340.8 | 272.1 | 368.7 | 190.3 | 344.1 | 396.1 | 250.0 |
| Isobutyric acid | 4.8 | 5.6 | 3.7 | 5.4 | 5.8 | 4.0 | 5.8 | 4.8 | 7.1 | 4.3 | 5.9 |
| Isoleucine | 45.8 | 42.8 | 37.5 | 41.9 | 39.6 | 42.8 | 46.9 | 43.6 | 48.0 | 36.2 | 49.8 |
| Lactic acid | 13805.8 | 12762.8 | 11478.2 | 14268.4 | 13143.7 | 12942.7 | 13780.8 | 13218.1 | 14093.5 | 12653.8 | 12950.3 |
| Leucine | 94.4 | 89.4 | 82.5 | 108.4 | 103.7 | 97.8 | 102.3 | 129.5 | 92.8 | 107.5 | 100.1 |
| myo-Inositol | 8837.2 | 8255.3 | 6927.5 | 8438.4 | 8570.4 | 8613.8 | 8369.2 | 7321.7 | 8547.8 | 8495.1 | 7909.3 |
| N-acetylaspartic acid | 7066.6 | 6276.9 | 5610.6 | 6705.0 | 6537.5 | 6310.4 | 7059.5 | 5717.1 | 7049.8 | 6924.5 | 6572.6 |
| NAD | 275.6 | 230.5 | 224.7 | 271.4 | 224.5 | 246.5 | 238.3 | 257.9 | 228.7 | 215.3 | 264.0 |
| NADH | 1.7 | 8.8 | 3.4 | 1.7 | 7.2 | 5.0 | 11.1 | 8.6 | 14.6 | 11.0 | 9 |
| Nicotinamide | 450.7 | 447.7 | 279.7 | 419.7 | 384.9 | 307.1 | 407.7 | 294.9 | 396.9 | 517.2 | 370.5 |
| Pantothenic acid | 58.5 | 47.6 | 41.2 | 55.8 | 47.3 | 43.3 | 71.8 | 31.6 | 63.7 | 65.1 | 70.8 |
| Phenylalanine | 82.4 | 70.1 | 48.6 | 72.2 | 55.4 | 56.5 | 69.3 | 74.7 | 59.8 | 58.4 | 95.2 |
| Phosphocholine | 607.0 | 547.6 | 450.7 | 572.1 | 571.8 | 576.8 | 614.0 | 535.6 | 573.1 | 609.5 | 600.2 |
| Phosphoethanolamine | 1528.0 | 1317.4 | 1178.8 | 1437.5 | 1437.3 | 1338.1 | 1426.8 | 1107.4 | 1336.1 | 1244.3 | 1323.8 |
| Pyruvic acid | 42.4 | 30.5 | 27.5 | 52.1 | 38.4 | 41.9 | 37.1 | 34.6 | 34.6 | 33.1 | 37.4 |
| scyllo-Inositol | 151.4 | 153.5 | 122.2 | 169.8 | 161.5 | 159 | 118.7 | 118.5 | 96.6 | 96.9 | 119.7 |
| Serine | 1051.7 | 978.7 | 841.3 | 978.1 | 971.6 | 960.4 | 960.3 | 777.5 | 1041.3 | 960.0 | 1009.3 |
| Succinic acid | 169.6 | 298.5 | 194.9 | 108.4 | 238.6 | 170.5 | 141.9 | 186.7 | 287.4 | 283.1 | 268.2 |
| Taurine | 6868.4 | 6058.3 | 5319.8 | 6564.8 | 6421.7 | 6300.2 | 6919.2 | 5599.9 | 6435.6 | 6238.5 | 6700.2 |
| Threonine | 441.2 | 348.5 | 320.2 | 536.0 | 419.9 | 358.4 | 420.3 | 288.8 | 451.5 | 422.7 | 377.9 |
| Tryptophan | 35.2 | 47.5 | 26.6 | 53.4 | 35.0 | 39.9 | 38.4 | 46.1 | 47.6 | 37.3 | 40.8 |
| Tyrosine | 88.9 | 64.7 | 62.3 | 70.2 | 61.5 | 77.8 | 75.9 | 61.4 | 84.2 | 68.0 | 69.6 |
| Uridine | 118.3 | 129.1 | 97.5 | 111.3 | 112.5 | 122.0 | 122.1 | 133.1 | 137.1 | 122.6 | 148.8 |
| UTP | 198.5 | 154.7 | 157.1 | 186.9 | 185.9 | 187.5 | 153.5 | 137.1 | 161.2 | 148.8 | 159.7 |
| Valine | 102.8 | 98.0 | 84.1 | 101.7 | 92.1 | 96.4 | 103.3 | 107.8 | 109.7 | 86.7 | 111.5 |
| Properties / Samples | OXYS3monthsS1 | OXYS3monthsS2 | OXYS3monthsS3 | OXYS3monthsS4 | OXYS3monthsS5 | OXYS3monthsS6 | Wistar3monthsS1 | Wistar3monthsS2 | Wistar3monthsS3 | Wistar3monthsS4 | Wistar3monthsS5 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Group | OXYS rat brain 3m | OXYS rat brain 3m | OXYS rat brain 3m | OXYS rat brain 3m | OXYS rat brain 3m | OXYS rat brain 3m | Wistar brain 3m | Wistar brain 3m | Wistar brain 3m | Wistar brain 3m | Wistar brain 3m |
| Description | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Species | Rat (Rattus norve… | Rat (Rattus norve… | Rat (Rattus norve… | Rat (Rattus norve… | Rat (Rattus norve… | Rat (Rattus norve… | Rat (Rattus norve… | Rat (Rattus norve… | Rat (Rattus norve… | Rat (Rattus norve… | Rat (Rattus norve… |
| Tissue | Brain | Brain | Brain | Brain | Brain | Brain | Brain | Brain | Brain | Brain | Brain |
| Diseases | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Gender | male | male | male | male | male | male | male | male | male | male | male |
| Origin | laboratory | laboratory | laboratory | laboratory | laboratory | laboratory | laboratory | laboratory | laboratory | laboratory | laboratory |
| Sample weight, mg | 108.1 | 112.3 | 145.6 | 104.1 | 112.0 | 113.5 | 115.3 | 129.7 | 116.5 | 115.9 | 118.1 |
| Sampling place | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia |
| Sampling date | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Age, months | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 |
| Time postmortem, min | 10 | 10 | 10 | 10 | 10 | 10 | 10 | 10 | 10 | 10 | 10 |