| Property | Value |
|---|---|
| Group name | Human AH kerat |
| Group ID | 424 |
| Related experiment | Human cornea and aqueous humour (keratoconus) |
| Samples | KeratAH1, KeratAH2, KeratAH3, KeratAH4, KeratAH5, KeratAH6, KeratAH7 |
| Species | Human (Homo sapiens) |
| Tissues | Aqueous humor |
| Diseases | Keratoconus |
| Date of creation | Sep 13, 2021 |
| Date of last modification | Sep 07, 2023 |
| Metabolites / Samples | KeratAH1 | KeratAH2 | KeratAH3 | KeratAH4 | KeratAH5 | KeratAH6 | KeratAH7 |
|---|---|---|---|---|---|---|---|
| 2-Hydroxy-3-methylbutyric acid | 6.4 | 6.8 | 10.6 | 10.6 | 2.6 | 8.0 | 2.1 |
| 2-Hydroxybutyric acid | 25.6 | 78.8 | 32.9 | 77.7 | 28.3 | 27.9 | 21.5 |
| 3-Hydroxybutyric acid | 21.3 | 112.5 | 20.8 | 85.4 | 38.6 | 46.5 | 37.6 |
| 3-Hydroxykynurenine | 0.4 | 0.2 | 0.2 | 0.1 | 0.2 | 0.2 | 0 |
| 3-Methyl-2-oxovaleric acid | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Acetic acid | 145.0 | 128.3 | 157.3 | 170.8 | 126.1 | 115.2 | 75.2 |
| Acetylcarnitine | 3.8 | 2.9 | 4.0 | 4.4 | 1.6 | 3.0 | 2.1 |
| Adenosine | 0.2 | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 | 0 |
| Adenosylhomocysteine | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0 |
| Alanine | 191.9 | 191.3 | 311.2 | 201.9 | 218.7 | 223.0 | 147.0 |
| AMP | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Arginine | 79.2 | 69.4 | 88.9 | 251.8 | 169.1 | 158.2 | 0 |
| Ascorbic acid | 409.4 | 337.5 | 484.1 | 452.9 | 295.9 | 234.1 | 58.1 |
| Asparagine | 35.8 | 19.8 | 36.2 | 33 | 36.8 | 28.3 | 0 |
| Aspartic acid | 1.5 | 0.3 | 1.2 | 3.4 | 7.4 | 1.9 | 0 |
| Benzoic acid | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Betaine | 9.4 | 8.3 | 10.7 | 17.3 | 7.2 | 10.6 | 6.8 |
| Carnitine | 14.5 | 11.7 | 19.0 | 24.3 | 11.3 | 11.3 | 14.7 |
| Choline | 6.8 | 6.8 | 7.8 | 9.3 | 4.9 | 7.3 | 5.1 |
| Citric acid | 38.4 | 20.3 | 43.2 | 38.8 | 28.3 | 35.3 | 29.1 |
| CMP | 0 | 0 | 0.0 | 0 | 0 | 0 | 0 |
| Creatine | 89.6 | 56.3 | 81.3 | 90.6 | 77.2 | 76.2 | 82.0 |
| Creatinine | 34.5 | 27 | 31.1 | 33.7 | 25.7 | 27.9 | 17.1 |
| Cystathionine | 0 | 0.0 | 0.1 | 0.0 | 0 | 0.0 | 0 |
| Cysteine | 7.1 | 4.8 | 6.3 | 10.4 | 10.2 | 7.0 | 0 |
| Cytidine | 1.7 | 0.9 | 1.2 | 1.0 | 0.8 | 0.7 | 0 |
| Deoxyguanosine | 1.4 | 0.1 | 0.2 | 0 | 0 | 0 | 0 |
| Formic acid | 24.7 | 20.0 | 22.5 | 22.5 | 19.8 | 20.4 | 23.9 |
| Fumaric acid | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Glucose | 3283.6 | 2520.1 | 3803.4 | 3960.0 | 2547.6 | 2582.5 | 2358.4 |
| Glutamic acid | 6.1 | 3.1 | 4.8 | 14.9 | 46.0 | 0 | 0 |
| Glutamine | 416.6 | 295.2 | 419.9 | 448.2 | 469.5 | 204.5 | 0 |
| Glycerol | 34.1 | 54 | 79.5 | 0 | 38.6 | 74.3 | 51.3 |
| Glycine | 14.1 | 15.8 | 32.9 | 17.1 | 10.6 | 20.4 | 13.0 |
| GMP | 0 | 0 | 0 | 0.0 | 0 | 0 | 0 |
| GSH | 0 | 0 | 0 | 0.3 | 0.1 | 1.5 | 0 |
| GSSG | 0 | 0 | 0 | 0.1 | 0.1 | 0.1 | 0 |
| Guanine | 0 | 0 | 0 | 0.1 | 0.0 | 0.1 | 0 |
| Guanosine | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Histidine | 51.2 | 42.8 | 70.9 | 44 | 48.9 | 48.3 | 31.5 |
| Hypotaurine | 0 | 0.5 | 0.8 | 0.7 | 0.9 | 0.7 | 0 |
| Hypoxanthine | 1.8 | 0.4 | 1.1 | 1.8 | 0.8 | 1.1 | 0 |
| Inosine | 3.7 | 2.0 | 2.1 | 2.5 | 1.7 | 1.6 | 0 |
| Isobutyric acid | 14.9 | 17.3 | 13.5 | 18.1 | 12.9 | 14.9 | 17.1 |
| Isoleucine | 64.0 | 49.5 | 77.8 | 56.9 | 41.2 | 53.9 | 44.4 |
| Ketoleucine | 37.1 | 5.4 | 7.8 | 17.1 | 7.7 | 8.7 | 4.4 |
| Kynurenine | 1.1 | 0.6 | 0.9 | 0.7 | 1.1 | 1.1 | 0 |
| Leucine | 170.6 | 157.5 | 190.2 | 152.7 | 102.9 | 148.6 | 170.9 |
| L-Lactic acid | 3539.5 | 5512.6 | 4840.7 | 4451.7 | 3319.6 | 3028.4 | 2495.2 |
| Lysine | 88.7 | 79.9 | 105.8 | 134.6 | 150.1 | 120.5 | 0 |
| Methionine | 29.7 | 16.3 | 30.7 | 32.4 | 31.5 | 30.1 | 0 |
| myo-Inositol | 93.8 | 92.3 | 114.1 | 129.4 | 92.6 | 83.6 | 51.3 |
| NAD | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Nicotinamide | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Ornithine | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Phenylalanine | 102.4 | 72 | 119.3 | 98.4 | 87.5 | 79.9 | 71.8 |
| Phosphocholine | 9.8 | 8.8 | 5.5 | 8.8 | 8.0 | 11.3 | 5.1 |
| Proline | 15.7 | 10.2 | 11.6 | 10.3 | 8.8 | 8.4 | 0 |
| Propylene glycol | 28.1 | 42.8 | 27.7 | 28.5 | 20.8 | 29.7 | 47.9 |
| Pyroglutamic acid | 27.4 | 19.6 | 26.3 | 35.2 | 33.0 | 24.5 | 0 |
| Pyruvic acid | 68.2 | 83.3 | 126.2 | 160.5 | 108.1 | 102.2 | 150.4 |
| Serine | 94.7 | 53.7 | 92.4 | 103 | 149.0 | 112.5 | 0 |
| Succinic acid | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Taurine | 46.6 | 31.8 | 24.5 | 40.5 | 41.1 | 48.3 | 0 |
| Threonine | 115.1 | 135 | 152.1 | 119.1 | 136.4 | 174.7 | 30.8 |
| Tryptophan | 25.6 | 29.3 | 31.1 | 23.8 | 24.5 | 26.0 | 20.5 |
| Tyrosine | 76.8 | 51.8 | 114.1 | 82.8 | 72.1 | 55.7 | 85.5 |
| UMP | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Uric acid | 33.7 | 36.1 | 40.7 | 72.9 | 28.5 | 46.5 | 0 |
| Uridine | 0 | 7.2 | 7.8 | 7.8 | 0 | 0 | 0 |
| Valine | 302.8 | 292.5 | 380.3 | 276.9 | 231.6 | 297.3 | 205.1 |
| Properties / Samples | KeratAH1 | KeratAH2 | KeratAH3 | KeratAH4 | KeratAH5 | KeratAH6 | KeratAH7 |
|---|---|---|---|---|---|---|---|
| Group | Human AH kerat | Human AH kerat | Human AH kerat | Human AH kerat | Human AH kerat | Human AH kerat | Human AH kerat |
| Description | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Species | Human (Homo sapie… | Human (Homo sapie… | Human (Homo sapie… | Human (Homo sapie… | Human (Homo sapie… | Human (Homo sapie… | Human (Homo sapie… |
| Tissue | Aqueous humor | Aqueous humor | Aqueous humor | Aqueous humor | Aqueous humor | Aqueous humor | Aqueous humor |
| Diseases | Keratoconus | Keratoconus | Keratoconus | Keratoconus | Keratoconus | Keratoconus | Keratoconus |
| Gender | male | male | male | male | female | male | female |
| Origin | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Sample weight, mg | 105.0 | 199.0 | 259.0 | 173.0 | 174.0 | 241.0 | 131.0 |
| Sampling place | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia | Novosibirsk, Russia |
| Sampling date | May 30, 2015 | May 20, 2015 | May 29, 2015 | June 18, 2015 | June 19, 2015 | July 2, 2015 | July 9, 2015 |
| Age, months | 264 | 612 | 300 | 468 | 348 | 288 | 348 |
| Time postmortem, min | 0 | 0 | 0 | 0 | 0 | 0 | 0 |